157869-15-3

Basic information

• Product Name: 2-((4-Methoxyphenyl)ethynyl)benzeneaMine
• Synonyms: 2-((4-Methoxyphenyl)ethynyl)benzeneaMine;BenzenaMine, 2-[(4-Methoxyphenyl)ethynyl]-;2-((4-Methoxyphenyl)ethynyl)aniline
• CAS NO: 157869-15-3
• Molecular Formula: C₁₅H₁₃NO
• Molecular Weight: 223.26982
• EINECS: -0
• Mol File: 157869-15-3.mol
• Article Data: 67

Chemical Properties

• Melting Point: 99-102 °C
• Boiling Point: 394.6±27.0 °C(Predicted)
• Appearance: /
• Density: 1.16±0.1 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 2.79±0.10(Predicted)
• CAS DataBase Reference: 2-((4-Methoxyphenyl)ethynyl)benzeneaMine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((4-Methoxyphenyl)ethynyl)benzeneaMine(157869-15-3)
• EPA Substance Registry System: 2-((4-Methoxyphenyl)ethynyl)benzeneaMine(157869-15-3)

Safety Data

• Hazardous Substances Data: 157869-15-3(Hazardous Substances Data)

Usage

General Description

2-((4-Methoxyphenyl)ethynyl)benzeneaMine, also known as 4-Methoxyphenylethynylaniline, is a chemical compound with the molecular formula C15H13NO. It is a benzene derivative that contains a methoxy group and an ethynyl group attached to a phenyl ring. 2-((4-Methoxyphenyl)ethynyl)benzeneaMine is commonly used in organic synthesis and as a building block in the pharmaceutical industry. It has been studied for its potential use in medicinal chemistry, particularly as a ligand for various biological targets. The chemical structure of 2-((4-Methoxyphenyl)ethynyl)benzeneaMine allows for the possibility of diverse chemical reactions and applications, making it a valuable compound in the field of organic chemistry.

Upstream product

• 52670-38-9 2-ethynylaniline 
• 62-53-3 aniline 
• 768-60-5 4-methoxyphenylacetylen 
• 348-54-9 2-Fluoroaniline 
• 3989-14-8 (4-methoxyphenylethynyl)trimethylsilane 
• 696-62-8 para-iodoanisole 
• 103529-16-4 2-[(trimethylsilyl)ethynyl]aniline 
• 615-43-0 2-iodophenylamine 
• 149457-45-4 4-(2-bromophenylethynyl)anisole 
• 615-36-1 2-bromoaniline 
• 623-12-1 4-chloromethoxybenzene 

Downstream Products

• 55164-80-2 3-(4-methoxy-phenyl)quinolin-2(1H)-one 
• 170956-93-1 3-(4-methoxybenzyl)-1,3-dihydroindol-2-one 
• 1220451-84-2 C₂₁H₂₁NO₃ 
• 54888-64-1 2-(4-methoxyphenethyl)aniline 
• 23646-34-6 4-hydroxy-3-(4-methoxyphenyl)quinolin-2(1H)-one 
• 1612824-69-7 (S)-2-(4-methoxyphenyl)-1-(1-phenylallyl)-1H-indole 
• 1329007-17-1 11-(4-methoxyphenyl)-6-phenyl-11H-indeno[1,2-c]quinolin-11-ol 
• 1298069-16-5 2-(4-methoxyphenyl)-3-((triisopropylsilyl)ethynyl)-1H-indole 
• 1285494-82-7 2-(4-methoxyphenyl)-3-(phenylthio)-1H-indole 
• 1285494-90-7 2-(4-methoxyphenyl)-3-(phenylselanyl)-1H-indole 
• 1285494-88-3 3-(4-bromophenylthio)-2-(4-methoxyphenyl)-1H-indole 
• 1285494-84-9 2-(4-methoxyphenyl)-3-(p-tolylthio)-1H-indole 
• 1285494-86-1 3-(4-chlorophenylthio)-2-(4-methoxyphenyl)-1H-indole 
• 1236003-89-6 (Z)-4-(4-methoxybenzylidene)-N,N-dimethyl-4H-benzo[d][1,3]thiazin-2-amine 

Relevant articles and documents

Gold-Catalyzed Cascade and Divergent Synthesis of Indolobenzazepines and Indoloquinolines from Nitrogen-Tethered 1,8-Diynes

We describe the divergent construction of two nitrogen-containing polycyclic systems by gold-catalyzed cycloisomerizations. The gold-catalyzed cascade hydroamination and 7-endo-dig-selective cycloisomerization of nitrogen-tethered 1,8-diynes yielded indol

Catalytic Enantioselective Aminopalladation–Heck Cascade

Domino processes initiated by intramolecular nucleopalladation of alkynes have been developed into powerful synthetic tools for the synthesis of functionalized heterocycles. However, a catalytic enantioselective version of this class of reactions remains

Nickel-catalyzed cyclization of 1,7-enynes for the selective synthesis of dihydrocyclobuta[c]quinolin-3-ones and benzo[b]azocin-2-ones

We herein described a nickel-catalyzed cyclization ofN-(o-ethynylaryl)acrylamides for the selective synthesis of dihydrocyclobuta[c]quinolin-3-ones and benzo[b]azocin-2-ones. The two varied products could be easily obtained by tuning the reaction temperature. This reaction features easy temperature-control, high efficiency, and gram-scale synthesis.