N-(3-benzyloxy-4-methoxyphenethyl)benzamide

Base Information

Chemical Name:N-(3-benzyloxy-4-methoxyphenethyl)benzamide
CAS No.:4008-65-5
Molecular Formula:C₂₃H₂₃NO₃
Molecular Weight:361.441
Hs Code.:
DSSTox Substance ID:DTXSID001203209

Synonyms:SCHEMBL11717434;SCDWRMYSUSRKNT-UHFFFAOYSA-N;DTXSID001203209;N-(3-benzyloxy-4-methoxyphenethyl)benzamide;N-[2-[4-Methoxy-3-(phenylmethoxy)phenyl]ethyl]benzamide;4008-65-5

Suppliers and Price of N-(3-benzyloxy-4-methoxyphenethyl)benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(3-benzyloxy-4-methoxyphenethyl)benzamide

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:361.16779360
Heavy Atom Count:27
Complexity:429

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)CCNC(=O)C2=CC=CC=C2)OCC3=CC=CC=C3

Technology Process of N-(3-benzyloxy-4-methoxyphenethyl)benzamide

There total 5 articles about N-(3-benzyloxy-4-methoxyphenethyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 36455-21-7
3-benzyloxy-4-methoxyphenylethylamine

: 98-88-4
benzoyl chloride

: 4008-65-5
N-(3-benzyloxy-4-methoxyphenylethyl)phenylformamide

Guidance literature:: With triethylamine; In ethanol; at 170 ℃; for 0.5h; Microwave irradiation;
DOI:10.1002/cmdc.201300412

Reference yield:

: 621-59-0
isovanillin

: 4008-65-5
N-(3-benzyloxy-4-methoxyphenylethyl)phenylformamide

Guidance literature:: Multi-step reaction with 4 steps

1: 94 percent / K₂CO₃ / ethanol / 5 h / Heating

2: 88 percent / NH₄OAc; AcOH / 4 h / Heating

3: 63 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 2 h / Heating

4: 5percent aq. NaOH / CH₂Cl₂ / 2 h / 20 °C

With lithium aluminium tetrahydride; ammonium acetate; potassium carbonate; acetic acid; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane; 4: Schotten-Baumann reaction;
DOI:10.1021/jm020831a

Reference yield:

: 63909-29-5,55507-05-6
3-benzyloxy-4-methoxy-β-nitrostyrene

: 4008-65-5
N-(3-benzyloxy-4-methoxyphenylethyl)phenylformamide

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 2 h / Heating

2: 5percent aq. NaOH / CH₂Cl₂ / 2 h / 20 °C

With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; dichloromethane; 2: Schotten-Baumann reaction;
DOI:10.1021/jm020831a