7-(N^α-Z-Glycylglycyl-L-argininamido)-4-(trifluoromethyl)coumarin Dihydrochloride

Base Information

• Chemical Name: 7-(N^α-Z-Glycylglycyl-L-argininamido)-4-(trifluoromethyl)coumarin Dihydrochloride
• CAS No.: 73389-51-2
• Molecular Formula: C₂₈H₃₀F₃N₇O₇*2ClH
• Molecular Weight: 706.506

Synonyms:7-(N^α-Z-Glycylglycyl-L-argininamido)-4-(trifluoromethyl)coumarin Dihydrochloride

Chemical Property of 7-(N^α-Z-Glycylglycyl-L-argininamido)-4-(trifluoromethyl)coumarin Dihydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-(N^α-Z-Glycylglycyl-L-argininamido)-4-(trifluoromethyl)coumarin Dihydrochloride

There total 4 articles about 7-(N^α-Z-Glycylglycyl-L-argininamido)-4-(trifluoromethyl)coumarin Dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

benzyloxycarbonylglycylglycine p-nitrophenyl ester (13574-81-7) + Arg-AFC (73496-42-1) → 7-(Nα-Z-Glycylglycyl-L-argininamido)-4-(trifluoromethyl)coumarin Dihydrochloride (73389-51-2)

Guidance literature:

With triethylamine; In pyridine; for 72h; Ambient temperature;

DOI:10.1021/jo01300a003

Reference yield:

CbzGlyGly (2566-19-0) + 7-(Nα-Z-L-Argininamido)-4-(trifluoromethyl)-coumarin Hydrochloride (73496-38-5) → 7-(Nα-Z-Glycylglycyl-L-argininamido)-4-(trifluoromethyl)coumarin Dihydrochloride (73389-51-2)

Guidance literature:

With 4-methyl-morpholine; palladium on activated charcoal; hydrogen; isobutyl chloroformate; Yield given. Multistep reaction;

DOI:10.1021/jo01300a003

Reference yield:

Z-Arg-OH (1234-35-1) → 7-(Nα-Z-Glycylglycyl-L-argininamido)-4-(trifluoromethyl)coumarin Dihydrochloride (73389-51-2)

Guidance literature:

Multi-step reaction with 2 steps

1: isobutyl chloroformate

2: 1.) H₂, Pd/C, 2.) N-methylmorpholine, isobutyl chloroformate

With 4-methyl-morpholine; palladium on activated charcoal; hydrogen; isobutyl chloroformate;

DOI:10.1021/jo01300a003

upstream raw materials:

CbzGlyGly

7-(N^α-Z-L-Argininamido)-4-(trifluoromethyl)-coumarin Hydrochloride

benzyloxycarbonylglycylglycine p-nitrophenyl ester

Arg-AFC

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 73389-51-2 7-(N^α-Z-Glycylglycyl-L-argininamido)-4-(trifluoromethyl)coumarin Dihydrochloride

Send

Send

Metric Ton KG G Pound L ML

Send

Send