C₁₆H₂₀O₆

Base Information

• Chemical Name: C₁₆H₂₀O₆
• CAS No.: 1446821-29-9
• Molecular Formula: C₁₆H₂₀O₆
• Molecular Weight: 308.331
• Mol file: 1446821-29-9.mol

Synonyms:C₁₆H₂₀O₆

Chemical Property of C₁₆H₂₀O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆H₂₀O₆

There total 5 articles about C₁₆H₂₀O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

tert-butyl (5R,2E)-5-[2-(3,5-dimethyloxyphenyl)acetoxy]hex-2-enoate (1446821-27-7) → C16H20O6 (1446821-29-9)

Guidance literature:

With 2,6-dimethylpyridine; trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at 0 - 20 ℃; for 1h; chemoselective reaction;

DOI:10.1016/j.tetlet.2013.05.068

Reference yield:

(2R)-pent-4-en-2-yl 2-bromoacetate (1446821-23-3) → C16H20O6 (1446821-29-9)

Guidance literature:

Multi-step reaction with 3 steps

1: palladium diacetate; potassium phosphate; tris-(o-tolyl)phosphine / tetrahydrofuran; water / 24 h / 20 °C

2: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 24 h

3: 2,6-dimethylpyridine; trimethylsilyl trifluoromethanesulfonate / dichloromethane / 1 h / 0 - 20 °C

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; 2,6-dimethylpyridine; potassium phosphate; trimethylsilyl trifluoromethanesulfonate; palladium diacetate; tris-(o-tolyl)phosphine; In tetrahydrofuran; dichloromethane; water;

DOI:10.1016/j.tetlet.2013.05.068

Reference yield:

(R)-pent-4-en-2-ol (64584-92-5) → C16H20O6 (1446821-29-9)

Guidance literature:

Multi-step reaction with 4 steps

1: pyridine / dichloromethane / 6 h / 20 °C

2: palladium diacetate; potassium phosphate; tris-(o-tolyl)phosphine / tetrahydrofuran; water / 24 h / 20 °C

3: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 24 h

4: 2,6-dimethylpyridine; trimethylsilyl trifluoromethanesulfonate / dichloromethane / 1 h / 0 - 20 °C

With pyridine; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; 2,6-dimethylpyridine; potassium phosphate; trimethylsilyl trifluoromethanesulfonate; palladium diacetate; tris-(o-tolyl)phosphine; In tetrahydrofuran; dichloromethane; water;

DOI:10.1016/j.tetlet.2013.05.068

upstream raw materials:

(2R)-pent-4-en-2-yl 2-(3,5-dimethoxyphenyl)acetate

tert-butyl (5R,2E)-5-[2-(3,5-dimethyloxyphenyl)acetoxy]hex-2-enoate

tert-butyl (2E,5R)-5-(2-bromoacetoxy)hex-2-enoate

(R)-pent-4-en-2-ol

Downstream raw materials:

C₁₆H₂₂O₆