64584-92-5

Basic information

• Product Name: (R)-(-)-PENTEN-2-OL
• Synonyms: (R)-(-)-2-HYDROXYPENT-4-ENE;(R)-(-)-PENTEN-2-OL;(r)-(-)-4-penten-2-ol;(1R)-1-Methyl-3-butene-1-ol;(2R)-4-Pentene-2-ol;(2R)-pent-4-en-2-ol
• CAS NO: 64584-92-5
• Molecular Formula: C₅H₁₀O
• Molecular Weight: 86.13
• Product Categories: API intermediates;Alcohols;Chiral Building Blocks;Organic Building Blocks
• Mol File: 64584-92-5.mol

Chemical Properties

• Boiling Point: 115-116 °C(lit.)
• Flash Point: 78 °F
• Appearance: /
• Density: 0.837 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.4240(lit.)
• PKA: 15.10±0.20(Predicted)
• Water Solubility: Soluble in water, 4.526 mg/L @ 25°C.
• CAS DataBase Reference: (R)-(-)-PENTEN-2-OL(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(-)-PENTEN-2-OL(64584-92-5)
• EPA Substance Registry System: (R)-(-)-PENTEN-2-OL(64584-92-5)

Safety Data

• Hazard Codes: H226
• Statements: 10
• RIDADR: UN 1987 3/PG 3
• WGK Germany: 3
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 64584-92-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(R)-(-)-PENTEN-2-OL is used as a reactant in the synthesis of aigialomycin D and its analogs, which are known to inhibit protein kinases related to cancer pathways. These compounds have potential applications in the development of novel anticancer drugs, targeting the specific protein kinases that play a crucial role in the growth and progression of cancer cells.
In the synthesis of aigialomycin D and its analogs, (R)-(-)-PENTEN-2-OL serves as a key intermediate, providing the necessary structural framework for the formation of the final product. (R)-(-)-PENTEN-2-OL's unique (R) configuration at the chiral center is essential for the biological activity of the synthesized compounds, as it ensures the correct stereochemistry for effective binding to the target protein kinases.
Furthermore, (R)-(-)-PENTEN-2-OL can be used as a starting material for the synthesis of other bioactive compounds with potential applications in the pharmaceutical industry. Its versatility as a building block allows for the development of a wide range of molecules with diverse biological activities, including those with potential therapeutic benefits.

Upstream product

• 111957-98-3 Pent-4-en-2-ol 
• 75-07-0 acetaldehyde 
• 77078-92-3 (-)-(1R,2S,3S,4S)-2,3-O-Allylborylen-2-endo-methyl-3-endo-phenyl-2-exo,3-exo-bornandiol 
• 7785-70-8 2,6,6-trimethylbicyclo[3.1.1]hept-2-ene 
• 1730-25-2 allylmagnesium bromide 
• 143143-11-7 2,2,2-Trifluoro-N-[(1R,2R)-1-methyl-2-((R)-1-methyl-but-3-enyloxy)-2-phenyl-ethyl]-acetamide 
• 108-22-5 Isopropenyl acetate 
• 2833-31-0 acetic acid 1-methylbut-3-enyl ester 
• 593-60-2 Vinyl bromide 
• 15448-47-2 (R)-propylene oxide 
• 75-56-9 methyloxirane 
• 116773-95-6 (R)-4-<(tert-butyldimethylsilyl)oxy>-1-pentene 
• 118629-75-7 (S)-2-hydroxypent-4-en-1-yl 4-methylbenzenesulfonate 
• 688-61-9 Triallylborane 

Downstream Products

• 300-85-6 3-Hydroxybutyric acid 
• 139079-91-7 (4R)-1-penten-4-yl-(αR)-α-methoxy-α-trifluoromethylphenylacetate 
• 335161-36-9 3-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-propionic acid 1-methyl-but-3-enyl ester 
• 634902-49-1 toluenesulfonic acid (R)-1-methyl-but-3-enyl ester 
• 873207-95-5 4,6-bis-(tert-butyl-dimethyl-silanyloxy)-3-chloro-2-methyl-benzoic acid 1-methyl-but-3-enyl ester 
• 149070-87-1 (S)-N-benzyl-2-methylpiperidine 
• 17924-92-4 zearalenone 
• 1225202-30-1 C₂₀H₃₀O₄ 
• 1176252-19-9 1-methoxy-4-{[(2R)-pent-4-en-2-yloxy]methyl}benzene 
• 1451476-59-7 (2R,3R,5R,6S)-2-(((2R,7R)-7-hydroxyoctan-2-yl)oxy)-6-methyltetrahydro-2H-pyran-3,5-diyl dibenzoate 
• 1451476-68-8 (2S,3R,5R,6R)-2-methyl-6-(((R)-7-oxooctan-2-yl)oxy)tetrahydro-2H-pyran-3,5-diyl dibenzoate 
• 959572-55-5 (2S,3R,5R,6R)-2-methyl-6-(((R)-5-oxohexan-2-yl)oxy)tetrahydro-2H-pyran-3,5-diyl dibenzoate 
• 1451475-90-3 (2R,3R,5R,6S)-2-(((R,E)-6-methoxy-6-oxohex-4-en-2-yl)oxy)-6-methyltetrahydro-2H-pyran-3,5-diyl dibenzoate 
• 1451476-02-0 (2R,3R,5R,6S)-2-(((R)-6-methoxy-6-oxohexan-2-yl)oxy)-6-methyltetrahydro-2H-pyran-3,5-diyl dibenzoate 

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