(1S,2R,5S)-2-Methyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-vinyl-cyclohexanecarboxylic acid

Base Information

Chemical Name:(1S,2R,5S)-2-Methyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-vinyl-cyclohexanecarboxylic acid
CAS No.:139694-44-3
Molecular Formula:C₁₄H₂₂O₄
Molecular Weight:254.326
Hs Code.:

Synonyms:(1S,2R,5S)-2-Methyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-vinyl-cyclohexanecarboxylic acid

Suppliers and Price of (1S,2R,5S)-2-Methyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-vinyl-cyclohexanecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1S,2R,5S)-2-Methyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-vinyl-cyclohexanecarboxylic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,2R,5S)-2-Methyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-vinyl-cyclohexanecarboxylic acid

There total 10 articles about (1S,2R,5S)-2-Methyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-vinyl-cyclohexanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 139694-43-2
(1S,2R,5S)-2-Methyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-vinyl-cyclohexanecarboxylic acid methyl ester

: 139694-44-3
(1S,2R,5S)-2-Methyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-vinyl-cyclohexanecarboxylic acid

Guidance literature:: With potassium hydroxide; In dimethyl sulfoxide; at 40 ℃;
DOI:10.1016/S0040-4039(00)77678-7

Reference yield:

: 139694-37-4
(1S,2R,5S)-5-Acetyl-2-methyl-2-vinyl-cyclohexanecarboxylic acid methyl ester

: 139694-44-3
(1S,2R,5S)-2-Methyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-vinyl-cyclohexanecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / p-TsOH / benzene / 80 °C

2: 93 percent / 20percent KOH / dimethylsulfoxide / 40 °C

With potassium hydroxide; toluene-4-sulfonic acid; In dimethyl sulfoxide; benzene;
DOI:10.1016/S0040-4039(00)77678-7

Reference yield:

: 139694-42-1
(1S,2R,5S,6R)-5-Acetyl-6-formyl-2-methyl-2-vinyl-cyclohexanecarboxylic acid methyl ester

: 139694-44-3
(1S,2R,5S)-2-Methyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-vinyl-cyclohexanecarboxylic acid

Guidance literature:: Multi-step reaction with 6 steps

1: 78 percent / NaClO₂, NaH₂PO₄, MeCH=CMe₂ / H₂O; 2-methyl-propan-2-ol / 23 °C

2: (COCl)2, pyridine / benzene / 5 °C

3: DMAP / benzene / 5 to 25 deg C

4: Bu₃SnH, AIBN / benzene / 50 °C

5: 89 percent / p-TsOH / benzene / 80 °C

6: 93 percent / 20percent KOH / dimethylsulfoxide / 40 °C

With pyridine; dmap; potassium hydroxide; sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; oxalyl dichloride; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; toluene-4-sulfonic acid; In water; dimethyl sulfoxide; tert-butyl alcohol; benzene;
DOI:10.1016/S0040-4039(00)77678-7