(1R,2S,3R,6S)-6-Acetyl-3-methyl-3-vinyl-cyclohexane-1,2-dicarboxylic acid 2-methyl ester

Base Information

Chemical Name:(1R,2S,3R,6S)-6-Acetyl-3-methyl-3-vinyl-cyclohexane-1,2-dicarboxylic acid 2-methyl ester
CAS No.:139694-36-3
Molecular Formula:C₁₄H₂₀O₅
Molecular Weight:268.31
Hs Code.:

Synonyms:(1R,2S,3R,6S)-6-Acetyl-3-methyl-3-vinyl-cyclohexane-1,2-dicarboxylic acid 2-methyl ester

Suppliers and Price of (1R,2S,3R,6S)-6-Acetyl-3-methyl-3-vinyl-cyclohexane-1,2-dicarboxylic acid 2-methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R,2S,3R,6S)-6-Acetyl-3-methyl-3-vinyl-cyclohexane-1,2-dicarboxylic acid 2-methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R,2S,3R,6S)-6-Acetyl-3-methyl-3-vinyl-cyclohexane-1,2-dicarboxylic acid 2-methyl ester

There total 5 articles about (1R,2S,3R,6S)-6-Acetyl-3-methyl-3-vinyl-cyclohexane-1,2-dicarboxylic acid 2-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 139694-42-1
(1S,2R,5S,6R)-5-Acetyl-6-formyl-2-methyl-2-vinyl-cyclohexanecarboxylic acid methyl ester

: 139694-36-3
(1R,2S,3R,6S)-6-Acetyl-3-methyl-3-vinyl-cyclohexane-1,2-dicarboxylic acid 2-methyl ester

Guidance literature:: With sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; In water; tert-butyl alcohol; at 23 ℃;
DOI:10.1016/S0040-4039(00)77678-7

Reference yield:

: (1S,2R,5S,6R)-5-Acetyl-6-((S)-1,2-dihydroxy-ethyl)-2-methyl-2-vinyl-cyclohexanecarboxylic acid methyl ester

: 139694-36-3
(1R,2S,3R,6S)-6-Acetyl-3-methyl-3-vinyl-cyclohexane-1,2-dicarboxylic acid 2-methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: NaIO₄, silica gel / H₂O; CH₂Cl₂

2: 78 percent / NaClO₂, NaH₂PO₄, MeCH=CMe₂ / H₂O; 2-methyl-propan-2-ol / 23 °C

With sodium chlorite; sodium periodate; sodium dihydrogenphosphate; 2-methyl-but-2-ene; silica gel; In dichloromethane; water; tert-butyl alcohol;
DOI:10.1016/S0040-4039(00)77678-7

Reference yield:

: 139694-40-9
(1S,2S,5R,6R)-5-Acetyl-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-formyl-2-methyl-cyclohexanecarboxylic acid methyl ester

: 139694-36-3
(1R,2S,3R,6S)-6-Acetyl-3-methyl-3-vinyl-cyclohexane-1,2-dicarboxylic acid 2-methyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 79 percent / Zn, Me₃Al / tetrahydrofuran / 20 °C

2: 83 percent / NaOMe / methanol / 50 °C

3: 80percent AcOH / 23 °C

4: NaIO₄, silica gel / H₂O; CH₂Cl₂

5: 78 percent / NaClO₂, NaH₂PO₄, MeCH=CMe₂ / H₂O; 2-methyl-propan-2-ol / 23 °C

With sodium chlorite; sodium periodate; sodium dihydrogenphosphate; 2-methyl-but-2-ene; trimethylaluminum; sodium methylate; silica gel; acetic acid; zinc; In tetrahydrofuran; methanol; dichloromethane; water; tert-butyl alcohol;
DOI:10.1016/S0040-4039(00)77678-7