Technology Process of 2-(2,3-dimethylphenyl)-1,3,2-dioxaborolane
There total 1 articles about 2-(2,3-dimethylphenyl)-1,3,2-dioxaborolane which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2,3-dimethylbromobenzene;
With
magnesium; sodium bis(2-methoxyethoxy)aluminium dihydride;
In
tetrahydrofuran;
at 50 ℃;
for 2h;
Inert atmosphere;
With
Trimethyl borate;
In
tetrahydrofuran;
at -25 - 30 ℃;
Inert atmosphere;
ethylene glycol;
In
toluene;
at 40 - 110 ℃;
for 8.75h;
- Guidance literature:
-
With
bis(acetonitrile)(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; water; sodium hydrogencarbonate;
In
tetrahydrofuran; methanol;
at 20 - 40 ℃;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: water; sodium hydrogencarbonate; bis(acetonitrile)(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate / tetrahydrofuran; methanol / 20 - 40 °C / Inert atmosphere
2.1: 5,5-dibromobarbituric acid; hydrogenchloride / tetrahydrofuran; water / 0.5 h / 60 - 65 °C / Large scale
3.1: ammonia / water; ethanol / 2 h / 120 °C / Autoclave; Large scale
3.2: pH 6 / Large scale
With
hydrogenchloride; 5,5-dibromobarbituric acid; bis(acetonitrile)(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; ammonia; water; sodium hydrogencarbonate;
In
tetrahydrofuran; methanol; ethanol; water;
