(+/-)-(E)-1-azido-7-(tert-butyldiphenylsilyloxy)-5-trimethylsilylhept-3-en-1-ol

Base Information

Chemical Name:(+/-)-(E)-1-azido-7-(tert-butyldiphenylsilyloxy)-5-trimethylsilylhept-3-en-1-ol
CAS No.:913975-81-2
Molecular Formula:C₂₆H₃₉N₃OSi₂
Molecular Weight:465.786
Hs Code.:

Synonyms:(+/-)-(E)-1-azido-7-(tert-butyldiphenylsilyloxy)-5-trimethylsilylhept-3-en-1-ol

Suppliers and Price of (+/-)-(E)-1-azido-7-(tert-butyldiphenylsilyloxy)-5-trimethylsilylhept-3-en-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (+/-)-(E)-1-azido-7-(tert-butyldiphenylsilyloxy)-5-trimethylsilylhept-3-en-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (+/-)-(E)-1-azido-7-(tert-butyldiphenylsilyloxy)-5-trimethylsilylhept-3-en-1-ol

There total 4 articles about (+/-)-(E)-1-azido-7-(tert-butyldiphenylsilyloxy)-5-trimethylsilylhept-3-en-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: methanesulfonic acid 7-(tert-butyl-diphenyl-silanyloxy)-5-trimethylsilanyl-hept-3-enyl ester

: 913975-81-2
(+/-)-(E)-1-azido-7-(tert-butyldiphenylsilyloxy)-5-trimethylsilylhept-3-en-1-ol

Guidance literature:: With sodium azide; In N,N-dimethyl-formamide; at 110 ℃; for 2h;
DOI:10.1021/ja063411+

Reference yield:

: 913975-65-2
(+/-)-(E)-7-(tert-butyldiphenylsilyloxy)-3-hydroxyhept-4-enyl pivalate

: 913975-81-2
(+/-)-(E)-1-azido-7-(tert-butyldiphenylsilyloxy)-5-trimethylsilylhept-3-en-1-ol

Guidance literature:: Multi-step reaction with 4 steps

1.1: 83 percent / triethylamine; 4-(dimethylamino)pyridine / tetrahydrofuran / 16 h / 20 °C

2.1: 1,1,3,3-tetramethylbutyl isocyanide / Pd(acac)2 / toluene / Heating

2.2: 59 percent / n-BuLi / tetrahydrofuran / 0.5 h / 0 °C

3.1: triethylamine / CH₂Cl₂ / 1 h / 0 °C

4.1: 0.11 g / sodium azide / dimethylformamide / 2 h / 110 °C

With dmap; sodium azide; 1,1,3,3-tetramethylbutane isonitrile; triethylamine; palladium(II) acetylacetonate; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/ja063411+

Reference yield:

: 913975-70-9
(+/-)-(E)-7-(tert-butyldiphenylsilyloxy)-3-(2,2,2-trimethyl-1,1-diphenyldisilyloxy)hept-4-enyl pivalate

: 913975-81-2
(+/-)-(E)-1-azido-7-(tert-butyldiphenylsilyloxy)-5-trimethylsilylhept-3-en-1-ol

Guidance literature:: Multi-step reaction with 3 steps

1.1: 1,1,3,3-tetramethylbutyl isocyanide / Pd(acac)2 / toluene / Heating

1.2: 59 percent / n-BuLi / tetrahydrofuran / 0.5 h / 0 °C

2.1: triethylamine / CH₂Cl₂ / 1 h / 0 °C

3.1: 0.11 g / sodium azide / dimethylformamide / 2 h / 110 °C

With sodium azide; 1,1,3,3-tetramethylbutane isonitrile; triethylamine; palladium(II) acetylacetonate; In dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/ja063411+