2-{3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidine-1-carbonyl}pyridin-4-ylmethyl methanesulfonate

Base Information

Chemical Name:2-{3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidine-1-carbonyl}pyridin-4-ylmethyl methanesulfonate
CAS No.:1255305-42-0
Molecular Formula:C₂₈H₃₀N₂O₆S
Molecular Weight:522.622
Hs Code.:

Synonyms:2-{3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidine-1-carbonyl}pyridin-4-ylmethyl methanesulfonate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-{3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidine-1-carbonyl}pyridin-4-ylmethyl methanesulfonate

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Technology Process of 2-{3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidine-1-carbonyl}pyridin-4-ylmethyl methanesulfonate

There total 1 articles about 2-{3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidine-1-carbonyl}pyridin-4-ylmethyl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1255304-34-7
{3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidin-1-yl}-4-hydroxymethylpyridin-2-yl-methanone

: 124-63-0
methanesulfonyl chloride

: 1255305-42-0
2-{3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidine-1-carbonyl}pyridin-4-ylmethyl methanesulfonate

Guidance literature:: With triethylamine; In chloroform; at 0 - 20 ℃;

Reference yield:

: 2425-41-4
5,5-dihydroxymethyl-2-phenyl-1,3-dioxane

: 1255305-42-0
2-{3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidine-1-carbonyl}pyridin-4-ylmethyl methanesulfonate

: 1255305-46-4
{3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidin-1-yl}-[4-(5-hydroxymethyl-2-phenyl[1,3]dioxan-5-ylmethoxymethyl)pyridin-2-yl]methanone

Guidance literature:: 5,5-dihydroxymethyl-2-phenyl-1,3-dioxane; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

2-{3-[4-(4-cyclopropylbenzyloxy)-3-methoxyphenyl]azetidine-1-carbonyl}pyridin-4-ylmethyl methanesulfonate; In N,N-dimethyl-formamide; at 20 ℃; for 1h;