Technology Process of 5’-bromo-3,4’-dihexyl-2,2’-bithiophene-5-aldehyde
There total 1 articles about 5’-bromo-3,4’-dihexyl-2,2’-bithiophene-5-aldehyde which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: trichlorophosphate / 0.5 h / 0 °C / Inert atmosphere
1.2: 12 h / 90 °C
2.1: tetrakis(triphenylphosphine) palladium(0) / toluene / 24 h / 110 °C / Inert atmosphere
3.1: acetic acid; N-Bromosuccinimide / chloroform / 12 h / 0 - 20 °C
With
N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium(0); acetic acid; trichlorophosphate;
In
chloroform; toluene;
2.1: |Stille Cross Coupling;
DOI:10.1002/asia.201601281
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0); caesium carbonate;
In
toluene;
for 16h;
Reflux;
Inert atmosphere;
DOI:10.3762/bjoc.9.122
- Guidance literature:
-
Multi-step reaction with 4 steps
1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / water; tetrahydrofuran / Inert atmosphere; Reflux
2: acetic acid; potassium iodide; potassium iodate / water / 80 °C / Inert atmosphere
3: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / water; tetrahydrofuran / Inert atmosphere; Reflux
4: acetic acid; ammonium acetate / Inert atmosphere; Reflux
With
potassium iodate; tetrakis(triphenylphosphine) palladium(0); ammonium acetate; potassium carbonate; acetic acid; potassium iodide;
In
tetrahydrofuran; water;
3: |Suzuki Coupling / 4: |Knoevenagel Condensation;
DOI:10.1039/c5tc03308j
