Technology Process of 5'-PhSNPPOC-dC(Ac)
There total 5 articles about 5'-PhSNPPOC-dC(Ac) which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
pyridine;
In
dichloromethane;
for 0.166667h;
Cooling with ice;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: bromine; iron / 20 °C / Cooling with ice
2: nitric acid; sulfuric acid / water / 20 °C / Cooling with ice
3: N-benzyl-trimethylammonium hydroxide / dimethyl sulfoxide; methanol / 6 h / 20 - 90 °C
4: potassium carbonate / N,N-dimethyl-formamide / 5 h / 140 - 160 °C
5: triethylamine / tetrahydrofuran / Cooling with ice
6: pyridine / dichloromethane / 0.17 h / Cooling with ice
With
pyridine; sulfuric acid; bromine; nitric acid; N-benzyl-trimethylammonium hydroxide; iron; potassium carbonate; triethylamine;
In
tetrahydrofuran; methanol; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: N-benzyl-trimethylammonium hydroxide / dimethyl sulfoxide; methanol / 6 h / 20 - 90 °C
2: potassium carbonate / N,N-dimethyl-formamide / 5 h / 140 - 160 °C
3: triethylamine / tetrahydrofuran / Cooling with ice
4: pyridine / dichloromethane / 0.17 h / Cooling with ice
With
pyridine; N-benzyl-trimethylammonium hydroxide; potassium carbonate; triethylamine;
In
tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;