N-methyl-2-(2-hydroxy-3,3-dimethylbutyl)benzamide-carboxyl-13C

Base Information

• Chemical Name: N-methyl-2-(2-hydroxy-3,3-dimethylbutyl)benzamide-carboxyl-13C
• CAS No.: 95387-90-9
• Molecular Formula: C₁₄H₂₁NO₂
• Molecular Weight: 236.315
• Mol file: 95387-90-9.mol

Synonyms:N-methyl-2-(2-hydroxy-3,3-dimethylbutyl)benzamide-carboxyl-13C

Chemical Property of N-methyl-2-(2-hydroxy-3,3-dimethylbutyl)benzamide-carboxyl-13C

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-methyl-2-(2-hydroxy-3,3-dimethylbutyl)benzamide-carboxyl-13C

There total 3 articles about N-methyl-2-(2-hydroxy-3,3-dimethylbutyl)benzamide-carboxyl-13C which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

pivalaldehyde (630-19-3) + N-methyl-o-toluamide-carboxyl-13C (95387-89-6) → N-methyl-2-(2-hydroxy-3,3-dimethylbutyl)benzamide-carboxyl-13C (95387-90-9)

Guidance literature:

With n-butyllithium; In hexane;

DOI:10.1021/ja00294a022

Reference yield:

-o-toluic acid (70838-82-3) → N-methyl-2-(2-hydroxy-3,3-dimethylbutyl)benzamide-carboxyl-13C (95387-90-9)

Guidance literature:

Multi-step reaction with 3 steps

1: thionyl chloride / 2 h / Heating

3: 81 percent / n-butyllithium / hexane

With n-butyllithium; thionyl chloride; In hexane;

DOI:10.1021/ja00294a022

Reference yield:

o-toluoyl-carboxyl-13C chloride (95387-99-8) → N-methyl-2-(2-hydroxy-3,3-dimethylbutyl)benzamide-carboxyl-13C (95387-90-9)

Guidance literature:

Multi-step reaction with 2 steps

2: 81 percent / n-butyllithium / hexane

With n-butyllithium; In hexane;

DOI:10.1021/ja00294a022

upstream raw materials:

pivalaldehyde

N-methyl-o-toluamide-carboxyl-13C

-o-toluic acid

o-toluoyl-carboxyl-13C chloride