tetraethyl((((1R,2S)-cyclohexane-1,2-diyl)bis(azanediyl))bis(carbonyl))bis(phosphonate)

Base Information

• Chemical Name: tetraethyl((((1R,2S)-cyclohexane-1,2-diyl)bis(azanediyl))bis(carbonyl))bis(phosphonate)
• CAS No.: 1035449-31-0
• Molecular Formula: C₁₆H₃₂N₂O₈P₂
• Molecular Weight: 442.386
• Mol file: 1035449-31-0.mol

Synonyms:tetraethyl((((1R,2S)-cyclohexane-1,2-diyl)bis(azanediyl))bis(carbonyl))bis(phosphonate)

Chemical Property of tetraethyl((((1R,2S)-cyclohexane-1,2-diyl)bis(azanediyl))bis(carbonyl))bis(phosphonate)

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of tetraethyl((((1R,2S)-cyclohexane-1,2-diyl)bis(azanediyl))bis(carbonyl))bis(phosphonate)

There total 3 articles about tetraethyl((((1R,2S)-cyclohexane-1,2-diyl)bis(azanediyl))bis(carbonyl))bis(phosphonate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

ethanol (64-17-5) + C8H16N2O2P2 → tetraethyl((((1R,2S)-cyclohexane-1,2-diyl)bis(azanediyl))bis(carbonyl))bis(phosphonate) (1035449-31-0)

Guidance literature:

With lithium perchlorate; tetra-(n-butyl)ammonium iodide; at 20 ℃; for 2h; Electrochemical reaction;

DOI:10.1039/c8nj05739g

Reference yield:

cis-cyclohexane-1,2-diamine (1436-59-5) + S-ethyl diethylphosphonothiolformate (163678-85-1) → diethyl cis-N-(2-aminocyclohexyl)carbamoylphosphonate + tetraethyl((((1R,2S)-cyclohexane-1,2-diyl)bis(azanediyl))bis(carbonyl))bis(phosphonate) (1035449-31-0)

Guidance literature:

In acetonitrile; at 20 ℃; for 1.5h; Title compound not separated from byproducts.;

DOI:10.1021/jm701087n

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) + cis-cyclohexane-1,2-diamine (1436-59-5) + S-ethyl diethylphosphonothiolformate (163678-85-1) → diethyl cis-N-(2-tert-butoxycarbonylaminocyclohexyl)carbamoylphosphonate + tetraethyl((((1R,2S)-cyclohexane-1,2-diyl)bis(azanediyl))bis(carbonyl))bis(phosphonate) (1035449-31-0)

Guidance literature:

cis-cyclohexane-1,2-diamine; S-ethyl diethylphosphonothiolformate; In acetonitrile; at 20 ℃; for 1.5h;

di-tert-butyl dicarbonate; In ethanol; at 20 ℃; for 2.5h; Further stages.;

DOI:10.1021/jm701087n

upstream raw materials:

cis-cyclohexane-1,2-diamine

S-ethyl diethylphosphonothiolformate

di-tert-butyl dicarbonate

ethanol