2,2,4-trimethyl-5-phenyl-2,3,4,5-tetrahydroisoxazole

Base Information

• Chemical Name: 2,2,4-trimethyl-5-phenyl-2,3,4,5-tetrahydroisoxazole
• CAS No.: 60980-85-0
• Molecular Formula: C₁₂H₁₇NO
• Molecular Weight: 191.273

Synonyms:2,2,4-trimethyl-5-phenyl-2,3,4,5-tetrahydroisoxazole

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Chemical Property of 2,2,4-trimethyl-5-phenyl-2,3,4,5-tetrahydroisoxazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2,4-trimethyl-5-phenyl-2,3,4,5-tetrahydroisoxazole

There total 1 articles about 2,2,4-trimethyl-5-phenyl-2,3,4,5-tetrahydroisoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetone (67-64-1) → 2,2,4-trimethyl-5-phenyl-2,3,4,5-tetrahydroisoxazole (60980-85-0)

Guidance literature:

In ethanol; at 25 ℃; for 0.25h;

DOI:10.1021/jo00213a014

Reference yield:

dichloroacethyl chloride (79-36-7) + 2,2,4-trimethyl-5-phenyl-2,3,4,5-tetrahydroisoxazole (60980-85-0) → 3-dichloroacetyl-2,2,4-trimethyl-5-phenyl-oxazolidine (60980-56-5)

Guidance literature:

With triethylamine; In benzene;

Reference yield:

2,2,4-trimethyl-5-phenyl-2,3,4,5-tetrahydroisoxazole (60980-85-0) → 1-phenyl-2-(isopropylamino)-1-propanol (4830-43-7,4831-17-8,53457-42-4,53457-43-5,91553-10-5,109361-28-6,112137-99-2)

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 25 ℃; for 0.333333h; Yield given;

DOI:10.1021/jo00213a014

upstream raw materials:

acetone

Downstream raw materials:

1-phenyl-2-(isopropylamino)-1-propanol

3-dichloroacetyl-2,2,4-trimethyl-5-phenyl-oxazolidine