N-(furan-2-ylmethyl)-4-methyl-4-N-prop-2-yn-1-ylbenzenesulfonamide

Base Information

• Chemical Name: N-(furan-2-ylmethyl)-4-methyl-4-N-prop-2-yn-1-ylbenzenesulfonamide
• CAS No.: 317834-58-5
• Molecular Formula: C₁₅H₁₅NO₃S
• Molecular Weight: 289.355
• Mol file: 317834-58-5.mol

Synonyms:N-(furan-2-ylmethyl)-4-methyl-4-N-prop-2-yn-1-ylbenzenesulfonamide

Chemical Property of N-(furan-2-ylmethyl)-4-methyl-4-N-prop-2-yn-1-ylbenzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(furan-2-ylmethyl)-4-methyl-4-N-prop-2-yn-1-ylbenzenesulfonamide

There total 8 articles about N-(furan-2-ylmethyl)-4-methyl-4-N-prop-2-yn-1-ylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

N-(furan-2-ylmethyl)prop-2-yn-1-amine (53175-35-2) + p-toluenesulfonyl chloride (98-59-9) → N-(furan-2-ylmethyl)-4-methyl-4-N-prop-2-yn-1-ylbenzenesulfonamide (317834-58-5)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 1h; Inert atmosphere;

DOI:10.1002/asia.201500246

Reference yield: 80.0%

(2-furyl)methyl alcohol (98-00-0,25212-86-6,93793-62-5) + 4-methyl-N-prop-2-ynylbenzenesulfonamide (55022-46-3) → N-(furan-2-ylmethyl)-4-methyl-4-N-prop-2-yn-1-ylbenzenesulfonamide (317834-58-5)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/ol901283m

Reference yield:

propargyl bromide (106-96-7) + N-tosylfurfurylamine (121564-33-8) → N-(furan-2-ylmethyl)-4-methyl-4-N-prop-2-yn-1-ylbenzenesulfonamide (317834-58-5)

Guidance literature:

With potassium carbonate; In acetonitrile; at 80 ℃; for 8h;

DOI:10.1016/j.molstruc.2019.07.032

upstream raw materials:

(2-furyl)methyl alcohol

4-methyl-N-prop-2-ynylbenzenesulfonamide

N-(furan-2-ylmethyl)prop-2-yn-1-amine

p-toluenesulfonyl chloride

Downstream raw materials:

N-(furan-2-ylmethyl)-4-methyl-N-(3-D)prop-2-yn-1-ylbenzenesulfonamide