(R)-1-[(R)-3-(3,4-Dimethyl-phenyl)-piperidin-1-yl]-2-methoxy-2-phenyl-ethanone

Base Information

Chemical Name:(R)-1-[(R)-3-(3,4-Dimethyl-phenyl)-piperidin-1-yl]-2-methoxy-2-phenyl-ethanone
CAS No.:334757-11-8
Molecular Formula:C₂₂H₂₇NO₂
Molecular Weight:337.462
Hs Code.:

Synonyms:(R)-1-[(R)-3-(3,4-Dimethyl-phenyl)-piperidin-1-yl]-2-methoxy-2-phenyl-ethanone

Suppliers and Price of (R)-1-[(R)-3-(3,4-Dimethyl-phenyl)-piperidin-1-yl]-2-methoxy-2-phenyl-ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (R)-1-[(R)-3-(3,4-Dimethyl-phenyl)-piperidin-1-yl]-2-methoxy-2-phenyl-ethanone

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (R)-1-[(R)-3-(3,4-Dimethyl-phenyl)-piperidin-1-yl]-2-methoxy-2-phenyl-ethanone

There total 1 articles about (R)-1-[(R)-3-(3,4-Dimethyl-phenyl)-piperidin-1-yl]-2-methoxy-2-phenyl-ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

: 3966-32-3
(R)-methoxyphenylacetic acid

: 3-(3,4-dimethylphenyl)piperidine

: 334757-11-8
(R)-1-[(R)-3-(3,4-Dimethyl-phenyl)-piperidin-1-yl]-2-methoxy-2-phenyl-ethanone

: 334757-10-7
(R)-1-[(S)-3-(3,4-Dimethyl-phenyl)-piperidin-1-yl]-2-methoxy-2-phenyl-ethanone

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; at 20 ℃; for 24h;
DOI:10.1016/S0960-894X(00)00633-8

Reference yield:

: 334757-11-8
(R)-1-[(R)-3-(3,4-Dimethyl-phenyl)-piperidin-1-yl]-2-methoxy-2-phenyl-ethanone

: 762230-69-3
(R)-3-(3,4-dimethylphenyl)piperidine

Guidance literature:: With potassium tert-butylate; water; In tetrahydrofuran; at 20 ℃; for 24h;
DOI:10.1016/S0960-894X(00)00633-8

Reference yield:

: 334757-11-8
(R)-1-[(R)-3-(3,4-Dimethyl-phenyl)-piperidin-1-yl]-2-methoxy-2-phenyl-ethanone

: (R)-3-(3,4-dimethylphenyl)-1-propylpiperidine

Guidance literature:: Multi-step reaction with 2 steps

1: t-BuOK; H₂O / tetrahydrofuran / 24 h / 20 °C

2: NaBH₃CN / methanol / 24 h / 20 °C

With potassium tert-butylate; water; sodium cyanoborohydride; In tetrahydrofuran; methanol;
DOI:10.1016/S0960-894X(00)00633-8