1,2-O-cyclohexylidene-3,4,5-tri-O-benzyl-6-O-(2-O-benzoyl-3,4-di-O-benzyl-6-O-[tert-butyldiphenylsilyl]-α-D-mannopyranosyl)-D-myo-inositol

Base Information

• Chemical Name: 1,2-O-cyclohexylidene-3,4,5-tri-O-benzyl-6-O-(2-O-benzoyl-3,4-di-O-benzyl-6-O-[tert-butyldiphenylsilyl]-α-D-mannopyranosyl)-D-myo-inositol
• CAS No.: 312538-75-3
• Molecular Formula: C₇₆H₈₂O₁₂Si
• Molecular Weight: 1215.57
• Mol file: 312538-75-3.mol

Synonyms:1,2-O-cyclohexylidene-3,4,5-tri-O-benzyl-6-O-(2-O-benzoyl-3,4-di-O-benzyl-6-O-[tert-butyldiphenylsilyl]-α-D-mannopyranosyl)-D-myo-inositol

Chemical Property of 1,2-O-cyclohexylidene-3,4,5-tri-O-benzyl-6-O-(2-O-benzoyl-3,4-di-O-benzyl-6-O-[tert-butyldiphenylsilyl]-α-D-mannopyranosyl)-D-myo-inositol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-O-cyclohexylidene-3,4,5-tri-O-benzyl-6-O-(2-O-benzoyl-3,4-di-O-benzyl-6-O-[tert-butyldiphenylsilyl]-α-D-mannopyranosyl)-D-myo-inositol

There total 1 articles about 1,2-O-cyclohexylidene-3,4,5-tri-O-benzyl-6-O-(2-O-benzoyl-3,4-di-O-benzyl-6-O-[tert-butyldiphenylsilyl]-α-D-mannopyranosyl)-D-myo-inositol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

1D-3,4,5-tri-O-benzyl-1,2-O-cyclohexylidene-myo-inositol (133162-49-9) + 3,4-di-O-benzyl-6-O-(tert-butyldiphenylsilyl)-β-D-mannopyranose 1,2-(pent-4-enyl orthobenzoate) (150772-61-5) → 1,2-O-cyclohexylidene-3,4,5-tri-O-benzyl-6-O-(2-O-benzoyl-3,4-di-O-benzyl-6-O-[tert-butyldiphenylsilyl]-α-D-mannopyranosyl)-D-myo-inositol (312538-75-3)

Guidance literature:

With N-iodo-succinimide; boron trifluoride diethyl etherate; at 0 ℃; for 0.5h;

DOI:10.1016/S0040-4039(00)01329-0

Reference yield: 74.0%

1,2-O-cyclohexylidene-3,4,5-tri-O-benzyl-6-O-(2-O-benzoyl-3,4-di-O-benzyl-6-O-[tert-butyldiphenylsilyl]-α-D-mannopyranosyl)-D-myo-inositol (312538-75-3) → 1,2-O-cyclohexylidene-3,4,5-tri-O-benzyl-6-O-(3,4-di-O-benzyl-6-O-[t-butyldiphenylsilyl]-α-D-mannopyranosyl)-D-myo-inositol

Guidance literature:

With methanol; sodium methylate; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1560/KDP7-D0BA-BN04-3H3A

Reference yield: 74.0%

trifluoromethylsulfonic anhydride (358-23-6) + 1,2-O-cyclohexylidene-3,4,5-tri-O-benzyl-6-O-(2-O-benzoyl-3,4-di-O-benzyl-6-O-[tert-butyldiphenylsilyl]-α-D-mannopyranosyl)-D-myo-inositol (312538-75-3) → C70H77F3O13SSi (312538-78-6)

Guidance literature:

With pyridine; dmap; In dichloromethane; at -75 - 20 ℃; for 3h;

DOI:10.1016/S0040-4039(00)01329-0

upstream raw materials:

1D-3,4,5-tri-O-benzyl-1,2-O-cyclohexylidene-myo-inositol

3,4-di-O-benzyl-6-O-(tert-butyldiphenylsilyl)-β-D-mannopyranose 1,2-(pent-4-enyl orthobenzoate)

Downstream raw materials:

C₇₀H₇₇F₃O₁₃SSi