3-chloro-N-(pyridin-3-ylmethyl)-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

Base Information

Chemical Name:3-chloro-N-(pyridin-3-ylmethyl)-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
CAS No.:5673-06-3
Molecular Formula:C₁₄H₁₀O₄
Molecular Weight:242.231
Hs Code.:
DSSTox Substance ID:DTXSID70367334
Wikidata:Q82153107

Synonyms:3-chloro-N-(pyridin-3-ylmethyl)-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide;CID 2257068;5673-06-3;CBMicro_027732;SCHEMBL1718948;DTXSID70367334;NTSILHIQKQNXJG-UHFFFAOYSA-N;BIM-0027643.P001;AB00092900-01

Suppliers and Price of 3-chloro-N-(pyridin-3-ylmethyl)-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-chloro-N-(pyridin-3-ylmethyl)-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.6g/cm³
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:437.0324933
Heavy Atom Count:29
Complexity:600

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CN=C1)CNC(=O)C2=NN3C(=CC(=NC3=C2Cl)C4=CC=CS4)C(F)(F)F

Technology Process of 3-chloro-N-(pyridin-3-ylmethyl)-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

There total 8 articles about 3-chloro-N-(pyridin-3-ylmethyl)-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 91-20-3,71998-51-1,72931-45-4
naphthalene

: 5673-03-0,5673-06-3,51869-91-1,51869-92-2,59068-42-7
Acenaphthen-trans-1,2-dicarbonsaeure

Guidance literature:: Multi-step reaction with 3 steps

1: Irradiation

2: Irradiation

3: KOH, EtOH

With potassium hydroxide; ethanol;
DOI:10.1021/jo01260a035

Reference yield:

: 5673-04-1,5673-22-3,51869-93-3,56137-60-1,93012-10-3
trans-1,2-dicarbomethoxy-1,2-dihydroacenaphthylene

: 5673-03-0,5673-06-3,51869-91-1,51869-92-2,59068-42-7
Acenaphthen-trans-1,2-dicarbonsaeure

Guidance literature:: With potassium hydroxide; ethanol;
DOI:10.1021/jo01260a035

Reference yield:

: 19988-65-9
Dimethyl 1-naphthylfumarate

: 5673-03-0,5673-06-3,51869-91-1,51869-92-2,59068-42-7
Acenaphthen-trans-1,2-dicarbonsaeure

Guidance literature:: Multi-step reaction with 2 steps

1: Irradiation

2: KOH, EtOH

With potassium hydroxide; ethanol;
DOI:10.1021/jo01260a035