1-[3-(3-Methoxyphenyl)-1-piperidinyl]-1-butanone

Base Information

Chemical Name:1-[3-(3-Methoxyphenyl)-1-piperidinyl]-1-butanone
CAS No.:79412-66-1
Molecular Formula:C₁₆H₂₃NO₂
Molecular Weight:261.364
Hs Code.:
DSSTox Substance ID:DTXSID101238198

Synonyms:1-[3-(3-Methoxyphenyl)-1-piperidinyl]-1-butanone;SCHEMBL7316755;DTXSID101238198;79412-66-1

Suppliers and Price of 1-[3-(3-Methoxyphenyl)-1-piperidinyl]-1-butanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-[3-(3-Methoxyphenyl)-1-piperidinyl]-1-butanone

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:261.172878976
Heavy Atom Count:19
Complexity:293

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCC(=O)N1CCCC(C1)C2=CC(=CC=C2)OC

Technology Process of 1-[3-(3-Methoxyphenyl)-1-piperidinyl]-1-butanone

There total 6 articles about 1-[3-(3-Methoxyphenyl)-1-piperidinyl]-1-butanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 88851-66-5
N-benzyl-3(S)-(3-methoxyphenyl)piperidine hydrochloride

: 79412-66-1,89874-54-4
1-[(S)-3-(3-Methoxy-phenyl)-piperidin-1-yl]-butan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / H₂ / 10percent Pd/C / ethanol / 28 h / 760 Torr / Ambient temperature

2: Et₃N / 0 °C

With hydrogen; triethylamine; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00374a016

Reference yield:

: 626-55-1,163928-56-1
3-Bromopyridine

: 79412-66-1
N-butyryl-3-(3-methoxyphenyl)piperidine

Guidance literature:: Multi-step reaction with 3 steps

1: dichlorobis(triphenylphosphine)nickel(II) / tetrahydrofuran / 24 h / Ambient temperature

2: H₂, conc. HCl / PtO₂ / methanol / 2585.7 Torr

3: NEt₃ / toluene / 0.5 h / Ambient temperature

With hydrogenchloride; bis(triphenylphosphine)nickel(II) chloride; hydrogen; triethylamine; platinum(IV) oxide; In tetrahydrofuran; methanol; toluene;
DOI:10.1021/jm00144a021

Reference yield:

: 4373-67-5
3-(3-methoxyphenyl)pyridine

: 79412-66-1
N-butyryl-3-(3-methoxyphenyl)piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: H₂, conc. HCl / PtO₂ / methanol / 2585.7 Torr

2: NEt₃ / toluene / 0.5 h / Ambient temperature

With hydrogenchloride; hydrogen; triethylamine; platinum(IV) oxide; In methanol; toluene;
DOI:10.1021/jm00144a021