(S)-2-Amino-N-[2-((S)-2-amino-3-phenyl-propionylamino)-phenyl]-3-phenyl-propionamide

Base Information

Chemical Name:(S)-2-Amino-N-[2-((S)-2-amino-3-phenyl-propionylamino)-phenyl]-3-phenyl-propionamide
CAS No.:247939-15-7
Molecular Formula:C₂₄H₂₆N₄O₂
Molecular Weight:402.496
Hs Code.:

Synonyms:(S)-2-Amino-N-[2-((S)-2-amino-3-phenyl-propionylamino)-phenyl]-3-phenyl-propionamide

Suppliers and Price of (S)-2-Amino-N-[2-((S)-2-amino-3-phenyl-propionylamino)-phenyl]-3-phenyl-propionamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (S)-2-Amino-N-[2-((S)-2-amino-3-phenyl-propionylamino)-phenyl]-3-phenyl-propionamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (S)-2-Amino-N-[2-((S)-2-amino-3-phenyl-propionylamino)-phenyl]-3-phenyl-propionamide

There total 6 articles about (S)-2-Amino-N-[2-((S)-2-amino-3-phenyl-propionylamino)-phenyl]-3-phenyl-propionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 197431-84-8
L-{1-[2-(2-tert-butoxycarbonylamino-3-phenyl-propionylamino)-phenylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester

: 247939-15-7
(S)-2-Amino-N-[2-((S)-2-amino-3-phenyl-propionylamino)-phenyl]-3-phenyl-propionamide

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 0.5h;
DOI:10.1016/S0040-4039(02)00687-1

Reference yield: 53.0%

: C₄₀H₃₈N₄O₆

: 247939-15-7
(S)-2-Amino-N-[2-((S)-2-amino-3-phenyl-propionylamino)-phenyl]-3-phenyl-propionamide

Guidance literature:: With 5%-palladium/activated carbon; hydrogen; In methanol; at 20 ℃; for 8h;
DOI:10.1021/acs.inorgchem.6b01066

Reference yield:

: 13734-34-4
N-tert-butoxycarbonyl-L-phenylalanine

: 247939-15-7
(S)-2-Amino-N-[2-((S)-2-amino-3-phenyl-propionylamino)-phenyl]-3-phenyl-propionamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1-ethyl-(3-dimethylaminopropyl)carbodiimide; 1-hydroxybenzotriazole hydrate; triethylamine / dimethylformamide

1.2: triethylamine / dimethylformamide

2.1: trifluoroacetic acid / CH₂Cl₂ / 0.5 h / 20 °C

With N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; 1-hydroxybenzotriazol-hydrate; triethylamine; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2005.03.067