(5-bromo-4-methoxy-2-(methoxymethoxy)benzyloxy)(tertbutyl)dimethylsilane

Base Information

Chemical Name:(5-bromo-4-methoxy-2-(methoxymethoxy)benzyloxy)(tertbutyl)dimethylsilane
CAS No.:1311270-87-7
Molecular Formula:C₁₆H₂₇BrO₄Si
Molecular Weight:391.377
Hs Code.:

Synonyms:(5-bromo-4-methoxy-2-(methoxymethoxy)benzyloxy)(tertbutyl)dimethylsilane

Suppliers and Price of (5-bromo-4-methoxy-2-(methoxymethoxy)benzyloxy)(tertbutyl)dimethylsilane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (5-bromo-4-methoxy-2-(methoxymethoxy)benzyloxy)(tertbutyl)dimethylsilane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (5-bromo-4-methoxy-2-(methoxymethoxy)benzyloxy)(tertbutyl)dimethylsilane

There total 4 articles about (5-bromo-4-methoxy-2-(methoxymethoxy)benzyloxy)(tertbutyl)dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 1153674-06-6
5-bromo-4-methoxy-2-methoxymethyloxybenzyl alcohol

: 18162-48-6
tert-butyldimethylsilyl chloride

: 1311270-87-7
(5-bromo-4-methoxy-2-(methoxymethoxy)benzyloxy)(tertbutyl)dimethylsilane

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 18h;
DOI:10.1016/j.tet.2011.03.059

Reference yield:

: 673-22-3
2-Hydroxy-4-methoxybenzaldehyde

: 1311270-87-7
(5-bromo-4-methoxy-2-(methoxymethoxy)benzyloxy)(tertbutyl)dimethylsilane

Guidance literature:: Multi-step reaction with 4 steps

1.1: bromine; acetic acid / 1 h / 0 - 20 °C

2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 0 °C

2.2: 2 h / 0 - 20 °C

3.1: sodium tetrahydroborate / ethanol / 2 h / 0 - 20 °C

4.1: 1H-imidazole / N,N-dimethyl-formamide / 18 h / 20 °C

With 1H-imidazole; sodium tetrahydroborate; bromine; sodium hydride; acetic acid; In ethanol; N,N-dimethyl-formamide; mineral oil;
DOI:10.1016/j.tet.2011.03.059

Reference yield:

: 5-bromo-4-methoxy-2-methoxymethoxybenzaldehyde

: 1311270-87-7
(5-bromo-4-methoxy-2-(methoxymethoxy)benzyloxy)(tertbutyl)dimethylsilane

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / ethanol / 2 h / 0 - 20 °C

2: 1H-imidazole / N,N-dimethyl-formamide / 18 h / 20 °C

With 1H-imidazole; sodium tetrahydroborate; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.tet.2011.03.059