4-[4-(2-Fluorophenyl)piperazin-1-yl]pyridin-3-amine

Base Information

Chemical Name:4-[4-(2-Fluorophenyl)piperazin-1-yl]pyridin-3-amine
CAS No.:78069-77-9
Molecular Formula:C15H17FN4
Molecular Weight:272.3207
Hs Code.:
NSC Number:131399
DSSTox Substance ID:DTXSID60999305
Wikidata:Q82992265

Synonyms:78069-77-9;NSC131399;4-[4-(2-fluorophenyl)piperazin-1-yl]pyridin-3-amine;BRN 4523822;3-Pyridinamine, 4-(4-(2-fluorophenyl)-1-piperazinyl)-;Piperazine, 1-(3-amino-4-pyridyl)-4-(o-fluorophenyl)-;DTXSID60999305;NSC 131399;NSC-131399

Suppliers and Price of 4-[4-(2-Fluorophenyl)piperazin-1-yl]pyridin-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-[4-(2-Fluorophenyl)piperazin-1-yl]pyridin-3-amine

Chemical Property:

Vapor Pressure:4.64E-09mmHg at 25°C
Boiling Point:471.5°C at 760 mmHg
Flash Point:238.9°C
Density:1.256g/cm³
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:272.14372472
Heavy Atom Count:20
Complexity:306

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1C2=C(C=NC=C2)N)C3=CC=CC=C3F

Technology Process of 4-[4-(2-Fluorophenyl)piperazin-1-yl]pyridin-3-amine

There total 3 articles about 4-[4-(2-Fluorophenyl)piperazin-1-yl]pyridin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 78069-76-8
1-(2-Fluoro-phenyl)-4-(3-nitro-pyridin-4-yl)-piperazine

: 78069-77-9
4-[4-(2-Fluoro-phenyl)-piperazin-1-yl]-pyridin-3-ylamine

Guidance literature:: With hydrogen; nickel; In ethanol; under 2327.2 Torr; Yield given; Ambient temperature;

Reference yield:

: 13091-23-1
4-chloro-3-nitropyridine

: 78069-77-9
4-[4-(2-Fluoro-phenyl)-piperazin-1-yl]-pyridin-3-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / toluene / Heating

2: H₂ / Raney Ni / ethanol / 2327.2 Torr / Ambient temperature

With hydrogen; triethylamine; nickel; In ethanol; toluene;

Reference yield:

: 1011-15-0
1-(o-fluorophenyl)piperazine

: 78069-77-9
4-[4-(2-Fluoro-phenyl)-piperazin-1-yl]-pyridin-3-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / toluene / Heating

2: H₂ / Raney Ni / ethanol / 2327.2 Torr / Ambient temperature

With hydrogen; triethylamine; nickel; In ethanol; toluene;