Technology Process of C40H44N2O
There total 6 articles about C40H44N2O which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2,2-bis[(5S,7S)-5,7-methano-6,6-dimethyl-5,6,7,8-tetrahydroquinolin-2-yl]propane;
With
n-butyllithium; N,N,N,N,-tetramethylethylenediamine; diisopropylamine;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 2h;
Inert atmosphere;
benzophenone;
In
tetrahydrofuran; hexane;
at -78 - 20 ℃;
Inert atmosphere;
DOI:10.1016/j.tetasy.2013.12.020
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: oxygen / UV-irradiation
2.1: titanium tetrachloride / dichloromethane / 4 h / -78 °C / Inert atmosphere
3.1: acetic acid; ammonium acetate / 12 h / Reflux; Inert atmosphere
4.1: n-butyllithium; diisopropylamine; N,N,N,N,-tetramethylethylenediamine / tetrahydrofuran; hexane / 2 h / -78 °C / Inert atmosphere
4.2: -78 - 20 °C / Inert atmosphere
With
n-butyllithium; N,N,N,N,-tetramethylethylenediamine; ammonium acetate; oxygen; titanium tetrachloride; acetic acid; diisopropylamine;
In
tetrahydrofuran; hexane; dichloromethane;
2.1: |Mukaiyama Aldol Addition;
DOI:10.1016/j.tetasy.2013.12.020
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: acetic acid; ammonium acetate / 12 h / Reflux; Inert atmosphere
2.1: n-butyllithium; diisopropylamine; N,N,N,N,-tetramethylethylenediamine / tetrahydrofuran; hexane / 2 h / -78 °C / Inert atmosphere
2.2: -78 - 20 °C / Inert atmosphere
With
n-butyllithium; N,N,N,N,-tetramethylethylenediamine; ammonium acetate; acetic acid; diisopropylamine;
In
tetrahydrofuran; hexane;
DOI:10.1016/j.tetasy.2013.12.020
