[3-(2-{2-[3-(4-benzoyl-benzylamino)-propoxy]-ethoxy}-ethoxy)-propyl]-carbamic acid tert-butyl ester

Base Information

• Chemical Name: [3-(2-{2-[3-(4-benzoyl-benzylamino)-propoxy]-ethoxy}-ethoxy)-propyl]-carbamic acid tert-butyl ester
• CAS No.: 908020-34-8
• Molecular Formula: C₂₉H₄₂N₂O₆
• Molecular Weight: 514.662

Synonyms:[3-(2-{2-[3-(4-benzoyl-benzylamino)-propoxy]-ethoxy}-ethoxy)-propyl]-carbamic acid tert-butyl ester

Chemical Property of [3-(2-{2-[3-(4-benzoyl-benzylamino)-propoxy]-ethoxy}-ethoxy)-propyl]-carbamic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [3-(2-{2-[3-(4-benzoyl-benzylamino)-propoxy]-ethoxy}-ethoxy)-propyl]-carbamic acid tert-butyl ester

There total 1 articles about [3-(2-{2-[3-(4-benzoyl-benzylamino)-propoxy]-ethoxy}-ethoxy)-propyl]-carbamic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

4-(bromomethyl)benzophenone (32752-54-8) + tert-butyl N-(3-{2-[2-(3-aminopropoxy)ethoxy]ethoxy}propyl)carbamate (194920-62-2) → [3-(2-{2-[3-(4-benzoyl-benzylamino)-propoxy]-ethoxy}-ethoxy)-propyl]-carbamic acid tert-butyl ester (908020-34-8)

Guidance literature:

With potassium carbonate; In dichloromethane; acetonitrile; for 17h;

DOI:10.1002/anie.200600743

Reference yield: 97.0%

[3-(2-{2-[3-(4-benzoyl-benzylamino)-propoxy]-ethoxy}-ethoxy)-propyl]-carbamic acid tert-butyl ester (908020-34-8) + bromoacetic acid methyl ester (96-32-2) → [(4-benzoyl-benzyl)-(3-{2-[2-(3-tert-butoxycarbonylamino-propoxy)-ethoxy]-ethoxy}-propyl)-amino]-acetic acid methyl ester (908020-36-0)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; for 17h;

DOI:10.1002/anie.200600743

Reference yield:

[3-(2-{2-[3-(4-benzoyl-benzylamino)-propoxy]-ethoxy}-ethoxy)-propyl]-carbamic acid tert-butyl ester (908020-34-8) → 5-(2-oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid {3-[2-(2-{3-[[(2-amino-ethylcarbamoyl)-methyl]-(4-benzoyl-benzyl)-amino]-propoxy}-ethoxy)-ethoxy]-propyl}-amide (908020-38-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 97 percent / N,N-diisopropylethylamine / CH₂Cl₂ / 17 h

2.1: trifluoroacetic acid / CH₂Cl₂ / 17 h

2.2: 1-hydroxy-1H-benzotriazole; N,N-diisopropylethylamine; diisopropylcarbodiimide / dimethylformamide / 48 h

2.3: 70 percent / 2 h

With N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane;

DOI:10.1002/anie.200600743

upstream raw materials:

4-(bromomethyl)benzophenone

tert-butyl N-(3-{2-[2-(3-aminopropoxy)ethoxy]ethoxy}propyl)carbamate

Downstream raw materials:

[(4-benzoyl-benzyl)-(3-{2-[2-(3-tert-butoxycarbonylamino-propoxy)-ethoxy]-ethoxy}-propyl)-amino]-acetic acid methyl ester

5-(2-oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid {3-[2-(2-{3-[[(2-amino-ethylcarbamoyl)-methyl]-(4-benzoyl-benzyl)-amino]-propoxy}-ethoxy)-ethoxy]-propyl}-amide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 908020-34-8 [3-(2-{2-[3-(4-benzoyl-benzylamino)-propoxy]-ethoxy}-ethoxy)-propyl]-carbamic acid tert-butyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send