N-{2-[2-(2-Methoxy-acetylamino)-phenoxy]-phenyl}-2-{2-[2-({2-[2-(2-methoxy-acetylamino)-phenoxy]-phenylcarbamoyl}-methoxy)-ethoxy]-ethoxy}-acetamide

Base Information

Chemical Name:N-{2-[2-(2-Methoxy-acetylamino)-phenoxy]-phenyl}-2-{2-[2-({2-[2-(2-methoxy-acetylamino)-phenoxy]-phenylcarbamoyl}-methoxy)-ethoxy]-ethoxy}-acetamide
CAS No.:181725-31-5
Molecular Formula:C₃₈H₄₂N₄O₁₁
Molecular Weight:730.772
Hs Code.:

Synonyms:N-{2-[2-(2-Methoxy-acetylamino)-phenoxy]-phenyl}-2-{2-[2-({2-[2-(2-methoxy-acetylamino)-phenoxy]-phenylcarbamoyl}-methoxy)-ethoxy]-ethoxy}-acetamide

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Chemical Property of N-{2-[2-(2-Methoxy-acetylamino)-phenoxy]-phenyl}-2-{2-[2-({2-[2-(2-methoxy-acetylamino)-phenoxy]-phenylcarbamoyl}-methoxy)-ethoxy]-ethoxy}-acetamide

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Technology Process of N-{2-[2-(2-Methoxy-acetylamino)-phenoxy]-phenyl}-2-{2-[2-({2-[2-(2-methoxy-acetylamino)-phenoxy]-phenylcarbamoyl}-methoxy)-ethoxy]-ethoxy}-acetamide

There total 4 articles about N-{2-[2-(2-Methoxy-acetylamino)-phenoxy]-phenyl}-2-{2-[2-({2-[2-(2-methoxy-acetylamino)-phenoxy]-phenylcarbamoyl}-methoxy)-ethoxy]-ethoxy}-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 31255-25-1
tetra-glycolic acid dichloride

: 181725-29-1
N-[2-(2-Amino-phenoxy)-phenyl]-2-methoxy-acetamide

: 181725-31-5
N-{2-[2-(2-Methoxy-acetylamino)-phenoxy]-phenyl}-2-{2-[2-({2-[2-(2-methoxy-acetylamino)-phenoxy]-phenylcarbamoyl}-methoxy)-ethoxy]-ethoxy}-acetamide

Guidance literature:: With triethylamine; In dichloromethane; for 16h; Ambient temperature;
DOI:10.1055/s-1996-4319

Reference yield:

: 24878-25-9
bis(2-aminophenyl)ether

: 181725-31-5
N-{2-[2-(2-Methoxy-acetylamino)-phenoxy]-phenyl}-2-{2-[2-({2-[2-(2-methoxy-acetylamino)-phenoxy]-phenylcarbamoyl}-methoxy)-ethoxy]-ethoxy}-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 48 percent / Et₃N / CH₂Cl₂ / 16 h / Ambient temperature

2: 82 percent / Et₃N / CH₂Cl₂ / 16 h / Ambient temperature

With triethylamine; In dichloromethane;
DOI:10.1055/s-1996-4319

Reference yield:

: 2217-65-4
bis(2-nitrophenyl)ether

: 181725-31-5
N-{2-[2-(2-Methoxy-acetylamino)-phenoxy]-phenyl}-2-{2-[2-({2-[2-(2-methoxy-acetylamino)-phenoxy]-phenylcarbamoyl}-methoxy)-ethoxy]-ethoxy}-acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / NH₂NH₂*H₂O / 10percent Pd/C / ethanol / 1 h / Heating

2: 48 percent / Et₃N / CH₂Cl₂ / 16 h / Ambient temperature

3: 82 percent / Et₃N / CH₂Cl₂ / 16 h / Ambient temperature

With hydrazine hydrate; triethylamine; palladium on activated charcoal; In ethanol; dichloromethane;
DOI:10.1055/s-1996-4319