ethyl 2-(benzo[d]thiazol-2-ylthio)acetate

Base Information

• Chemical Name: ethyl 2-(benzo[d]thiazol-2-ylthio)acetate
• CAS No.: 24044-88-0
• Molecular Formula: C11H11 N O2 S2
• Molecular Weight: 253.346
• Mol file: 24044-88-0.mol

Synonyms:Aceticacid, (2-benzothiazolylthio)-, ethyl ester (6CI,7CI,8CI,9CI); Ethyl2-benzothiazolylthioacetate; Ethyl S-2-benzothiazolylmercaptoacetate

Chemical Property of ethyl 2-(benzo[d]thiazol-2-ylthio)acetate

Chemical Property:

• Melting Point: 42-44 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 373.4±44.0 °C(Predicted)
• PKA: 0.12±0.10(Predicted)
• PSA: 92.73000
• Density: 1.33±0.1 g/cm3(Predicted)
• LogP: 2.95150

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl 2-(benzo[d]thiazol-2-ylthio)acetate

There total 2 articles about ethyl 2-(benzo[d]thiazol-2-ylthio)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

diazoacetic acid ethyl ester (623-73-4) + 2-((E)-8-Benzyloxy-2,6-dimethyl-oct-2-enylsulfanyl)-benzothiazole → ethyl 2-(benzo[d]thiazol-2-ylthio)acetate (24044-88-0) + (E)-8-Benzyloxy-3-isopropenyl-6-methyl-oct-2-enoic acid ethyl ester

Guidance literature:

With tetrakis(actonitrile)copper(I) hexafluorophosphate; In dichloromethane; Ambient temperature;

DOI:10.1016/S0040-4039(97)00587-X

Reference yield:

diazoacetic acid ethyl ester (623-73-4) + 2-[(E)-3-phenyl-2-propenylsulfanyl]-1,3-benzothiazole (69747-26-8) → (Z)-3-Phenyl-penta-2,4-dienoic acid ethyl ester (190845-64-8) + ethyl 2-(benzo[d]thiazol-2-ylthio)acetate (24044-88-0)

Guidance literature:

With tetrakis(actonitrile)copper(I) hexafluorophosphate; In dichloromethane; Ambient temperature;

DOI:10.1016/S0040-4039(97)00587-X

Reference yield: 94.0%

ethyl 2-(benzo[d]thiazol-2-ylthio)acetate (24044-88-0) → 2-benzthiazole thioacetic acid (6295-57-4)

Guidance literature:

With water; sodium hydroxide; In methanol; at 20 ℃; for 19h;

DOI:10.1055/s-0029-1219185

upstream raw materials:

diazoacetic acid ethyl ester

2-[(E)-3-phenyl-2-propenylsulfanyl]-1,3-benzothiazole

Downstream raw materials:

2-benzthiazole thioacetic acid

Potassium (benzothiazol-2-ylthio)acetate

[(1,3-benzothiazol-2-ylthio)acetyl]hydrazine

(Z)-ethyl 3-(4-methoxyphenyl)acrylate