N^α-(benzyloxycarbonyl)-N^δ-cyanoornithine methyl ester

Base Information

• Chemical Name: N^α-(benzyloxycarbonyl)-N^δ-cyanoornithine methyl ester
• CAS No.: 125735-05-9
• Molecular Formula: C₁₅H₁₉N₃O₄
• Molecular Weight: 305.334
• Mol file: 125735-05-9.mol

Synonyms:N^α-(benzyloxycarbonyl)-N^δ-cyanoornithine methyl ester

Chemical Property of N^α-(benzyloxycarbonyl)-N^δ-cyanoornithine methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N^α-(benzyloxycarbonyl)-N^δ-cyanoornithine methyl ester

There total 4 articles about N^α-(benzyloxycarbonyl)-N^δ-cyanoornithine methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Nα-(benzyloxycarbonyl)-L-citrulline methyl ester (89499-13-8) → Nα-(benzyloxycarbonyl)-Nδ-cyanoornithine methyl ester (125735-05-9)

Guidance literature:

With pyridine; p-toluenesulfonyl chloride; for 3h; Ambient temperature;

DOI:10.1021/jo00295a022

Reference yield:

2-Amino-5-ureido-pentanoic acid (372-75-8,627-77-0,7005-93-8,13594-51-9) → Nα-(benzyloxycarbonyl)-Nδ-cyanoornithine methyl ester (125735-05-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 1 N NaOH / 0.5 h / Ambient temperature

3: 100 percent / p-toluenesulfonyl chloride, pyridine / 3 h / Ambient temperature

With pyridine; sodium hydroxide; p-toluenesulfonyl chloride;

DOI:10.1021/jo00295a022

Reference yield:

Nα-(benzyloxycarbonyl)-L-citrulline (6692-89-3,13594-52-0) → Nα-(benzyloxycarbonyl)-Nδ-cyanoornithine methyl ester (125735-05-9)

Guidance literature:

Multi-step reaction with 2 steps

2: 100 percent / p-toluenesulfonyl chloride, pyridine / 3 h / Ambient temperature

With pyridine; p-toluenesulfonyl chloride;

DOI:10.1021/jo00295a022

upstream raw materials:

N^α-(benzyloxycarbonyl)-L-citrulline methyl ester

2-Amino-5-ureido-pentanoic acid

N^α-(benzyloxycarbonyl)-L-citrulline

L-ornithine hydrochloride

Downstream raw materials:

N^α-(benzyloxycarbonyl)-L-citrulline methyl ester

2-Benzyloxycarbonylamino-5-(5-methoxycarbonylmethyl-4-oxo-4,5-dihydro-1H-imidazol-2-ylamino)-pentanoic acid methyl ester

2-Benzyloxycarbonylamino-5-(2-imino-4-methoxycarbonylmethyl-5-oxo-imidazolidin-1-yl)-pentanoic acid methyl ester

α-(benzyloxycarbonyl)arginino>succinic acid trimethyl ester

Refernces