89499-13-8

Basic information

• Product Name: N^α-(benzyloxycarbonyl)-L-citrulline methyl ester
• Synonyms: N^α-(benzyloxycarbonyl)-L-citrulline methyl ester
• CAS NO: 89499-13-8
• Molecular Weight: 323.349
• Mol File: 89499-13-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N^α-(benzyloxycarbonyl)-L-citrulline methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N^α-(benzyloxycarbonyl)-L-citrulline methyl ester(89499-13-8)
• EPA Substance Registry System: N^α-(benzyloxycarbonyl)-L-citrulline methyl ester(89499-13-8)

Safety Data

• Hazardous Substances Data: 89499-13-8(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 6692-89-3 N^α-benzyloxy-carbonyl-L-citrulline 
• 3184-13-2 L-ornithine hydrochloride 
• 372-75-8 2-Amino-5-ureido-pentanoic acid 
• 125735-05-9 N^α-(benzyloxycarbonyl)-N^δ-cyanoornithine methyl ester 
• 32213-95-9 DL-aspartic acid dimethyl ester hydrochloride 
• 6692-89-3 N^α-(benzyloxycarbonyl)-L-citrulline 

Downstream Products

• 125735-06-0 α-(benzyloxycarbonyl)arginino>succinic acid trimethyl ester 
• 125735-11-7 2-Benzyloxycarbonylamino-5-(2-imino-4-methoxycarbonylmethyl-5-oxo-imidazolidin-1-yl)-pentanoic acid methyl ester 
• 125735-10-6 2-Benzyloxycarbonylamino-5-(5-methoxycarbonylmethyl-4-oxo-4,5-dihydro-1H-imidazol-2-ylamino)-pentanoic acid methyl ester 
• 125735-05-9 N^α-(benzyloxycarbonyl)-N^δ-cyanoornithine methyl ester 
• 89499-14-9 methyl N^α-benzyloxycarbonyl-N^ω-carbamoyl-L-citrullinate 

Relevant articles and documents

Urea cycle: Chemical simulation of arginine biosynthesis

We have successfully simulated the salient features of the urea cycle. In this effort an appropriately protected ornithine was transformed to citrulline, via use of a novel amide transfer reagent; the citrulline, in turn, was converted into argininosuccinate which necessitated a new activation procedure to enable acceptance of dimethyl aspartate. Fragmentation of argininosuccinate under carefully controlled conditions afforded arginine. The final step in the cycle, namely, the hydrolysis of arginine to urea and ornithine, has already been accomplished. Amino group transfer from aspartate has also been demonstrated in the conversion of hypoxanthine to adenine.