1-phenylpropan-2-yl chloroformate

Base Information

• Chemical Name: 1-phenylpropan-2-yl chloroformate
• CAS No.: 65935-44-6
• Molecular Formula: C₁₀H₁₁ClO₂
• Molecular Weight: 198.649
• Mol file: 65935-44-6.mol

Synonyms:1-phenylpropan-2-yl chloroformate

Chemical Property of 1-phenylpropan-2-yl chloroformate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-phenylpropan-2-yl chloroformate

There total 2 articles about 1-phenylpropan-2-yl chloroformate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bis(trichloromethyl) carbonate (32315-10-9) + 3-phenyl-2-propanol (698-87-3,14898-87-4) → 1-phenylpropan-2-yl chloroformate (65935-44-6)

Guidance literature:

With pyridine; In toluene; at 0 - 20 ℃;

DOI:10.1021/jacs.0c04448

Reference yield:

phosgene (75-44-5) + 3-phenyl-2-propanol (698-87-3,14898-87-4) → 1-phenylpropan-2-yl chloroformate (65935-44-6)

Guidance literature:

DOI:10.1016/S0040-4020(01)92940-0

Reference yield: 84.0%

1-phenylpropan-2-yl chloroformate (65935-44-6) + 2-(4-methoxyphenyl)-4-methyl-5-oxo-4,5-dihydrooxazole (99553-79-4,108509-76-8,85380-77-4) → 2-(4-methoxyphenyl)-4-methyloxazol-5-yl 1-phenylpropan-2-yl carbonate (1017848-60-0)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1021/jo702720a

upstream raw materials:

phosgene

3-phenyl-2-propanol

bis(trichloromethyl) carbonate

Downstream raw materials:

1-Phenyl-2-propyl-β-phenylisobutyrylcarbonat

2-(4-methoxyphenyl)-4-methyloxazol-5-yl 1-phenylpropan-2-yl carbonate

4-benzyl-2-(4-methoxyphenyl)oxazol-5-yl 1-phenylpropan-2-yl carbonate

syn-5-methyl-4-phenyloxazolidin-2-one