N'-benzyloxy-5--1-(methoxymethyl)-1H-imidazole-4-carboxamidine

Base Information

Chemical Name:N'-benzyloxy-5--1-(methoxymethyl)-1H-imidazole-4-carboxamidine
CAS No.:119139-07-0
Molecular Formula:C₂₀H₂₉N₅O₅
Molecular Weight:419.481
Hs Code.:

N'-benzyloxy-5-<N-(2,2-diethoxyethyl)formamido>-1-(methoxymethyl)-1H-imidazole-4-carboxamidine

Synonyms:N'-benzyloxy-5--1-(methoxymethyl)-1H-imidazole-4-carboxamidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N'-benzyloxy-5--1-(methoxymethyl)-1H-imidazole-4-carboxamidine

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Technology Process of N'-benzyloxy-5--1-(methoxymethyl)-1H-imidazole-4-carboxamidine

There total 2 articles about N'-benzyloxy-5--1-(methoxymethyl)-1H-imidazole-4-carboxamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 119139-06-9
N'-benzyloxy-5-formamido-1-(methoxymethyl)-1H-imidazole-4-carboxamidine

: 51806-20-3
1,1-diethoxy-2-iodoethane

: 119139-07-0
N'-benzyloxy-5--1-(methoxymethyl)-1H-imidazole-4-carboxamidine

Guidance literature:: With 18-crown-6 ether; potassium carbonate; In N,N-dimethyl-formamide; at 30 ℃; for 27h;
DOI:10.3987/COM-88-4519

Reference yield:

: 1-benzyloxy-9-(methoxymethyl)adenine perchlorate

: 119139-07-0
N'-benzyloxy-5--1-(methoxymethyl)-1H-imidazole-4-carboxamidine

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / NaOH, H₂O / 5 h / 40 °C

2: 1.) K₂CO₃, 2.) 18-crown-6 / 1.) DMF, RT, 1 h, 2.) DMF, 30 deg C, 27 h

With sodium hydroxide; 18-crown-6 ether; water; potassium carbonate;
DOI:10.1248/cpb.42.1231