Technology Process of <(+/-)-trans>-2-methyl-8-phenyl-4-cycloocten-1-one
There total 4 articles about <(+/-)-trans>-2-methyl-8-phenyl-4-cycloocten-1-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 43 percent / boron trifluoride etherate / cyclohexane; diethyl ether; tetrahydrofuran / 0.17 h / -78 °C
2: 76 percent / Jones' reagent (chromium trioxide, sulfuric acid) / acetone / 0.25 h / 0 °C
3: 1.) lithium diisopropylamide / 1.) hexane, THF, -78 deg C, 30 min, 2.) a.) -78 deg C, 1 h, b.) from -78 deg C to RT, 1 h
With
Jones' reagent (chromium trioxide, sulfuric acid); boron trifluoride diethyl etherate; lithium diisopropyl amide;
In
tetrahydrofuran; diethyl ether; cyclohexane; acetone;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 76 percent / Jones' reagent (chromium trioxide, sulfuric acid) / acetone / 0.25 h / 0 °C
2: 1.) lithium diisopropylamide / 1.) hexane, THF, -78 deg C, 30 min, 2.) a.) -78 deg C, 1 h, b.) from -78 deg C to RT, 1 h
With
Jones' reagent (chromium trioxide, sulfuric acid); lithium diisopropyl amide;
In
acetone;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 43 percent / boron trifluoride etherate / cyclohexane; diethyl ether; tetrahydrofuran / 0.17 h / -78 °C
2: 76 percent / Jones' reagent (chromium trioxide, sulfuric acid) / acetone / 0.25 h / 0 °C
3: 1.) lithium diisopropylamide / 1.) hexane, THF, -78 deg C, 30 min, 2.) a.) -78 deg C, 1 h, b.) from -78 deg C to RT, 1 h
With
Jones' reagent (chromium trioxide, sulfuric acid); boron trifluoride diethyl etherate; lithium diisopropyl amide;
In
tetrahydrofuran; diethyl ether; cyclohexane; acetone;
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