N,O3'-dibenzoylgeMcitabine

Base Information

Chemical Name:N,O3'-dibenzoylgeMcitabine
CAS No.:1020657-43-5
Molecular Formula:C₂₃H₁₉F₂N₃O₆
Molecular Weight:471.417
Hs Code.:

Synonyms:N⁴,O-^3’-dibenzoyl-2’,2’-difluoro-2-deoxycytidine

Suppliers and Price of N,O3'-dibenzoylgeMcitabine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-?Benzoyl-?2''-?deoxy-?2'',?2''-?difluorocytidine3’-Benzoate
50mg
$ 1190.00

Medical Isotopes, Inc.
N-Benzoyl-2??-deoxy-2??,2??-difluorocytidine3??-Benzoate
5 mg
$ 650.00

Total 3 raw suppliers

Chemical Property of N,O3'-dibenzoylgeMcitabine

Chemical Property:

Melting Point:195-197oC
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly, Heated)

Purity/Quality:

96% ^*data from raw suppliers

N-?Benzoyl-?2''-?deoxy-?2'',?2''-?difluorocytidine3’-Benzoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses N-Benzoyl-2''-deoxy-2'',2''-difluorocytidine 3’-Benzoate is an intermediate in the synthesis of Gemcitabine (G305000) metabolites.

Technology Process of N,O3'-dibenzoylgeMcitabine

There total 7 articles about N,O3'-dibenzoylgeMcitabine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1151528-37-8
C₂₉H₃₃F₂N₃O₆Si

: 1020657-43-5
N⁴,O-^3’-dibenzoyl-2’,2’-difluoro-2-deoxycytidine

Guidance literature:: C₂₉H₃₃F₂N₃O₆Si; With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 ℃; for 3.5h;

With acetic acid;
DOI:10.1016/j.tetlet.2013.11.018

Reference yield: 55.0%

: 1421929-71-6
C₃₀H₂₉F₂N₃O₆

: 98-88-4
benzoyl chloride

: 1020657-43-5
N⁴,O-^3’-dibenzoyl-2’,2’-difluoro-2-deoxycytidine

Guidance literature:: C₃₀H₂₉F₂N₃O₆; benzoyl chloride; With pyridine; at 0 - 20 ℃; for 2h;

With toluene-4-sulfonic acid; In dichloromethane; at 20 ℃; for 2h;