Technology Process of 1,5-diphenyl-2-amino-3-pentanone hydrobromide
There total 5 articles about 1,5-diphenyl-2-amino-3-pentanone hydrobromide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen bromide;
In
methanol;
for 1h;
Heating;
DOI:10.1021/jo00367a026
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 95 percent / sodium azide / dimethylsulfoxide / 0.5 h / 10 °C
2: 76 percent / HCl, H2 / 10percent Pd/C / methanol / 5 h / 2327.2 Torr / Ambient temperature
3: 98 percent / sodium formate / 1 h / Ambient temperature
4: 1.) NaH / 1.) DMF, 0 deg C, 30 min, 2.) DMF, 0 deg C, 1 h
5: 77 percent / methanolic HBr / methanol / 1 h / Heating
With
hydrogenchloride; sodium azide; hydrogen bromide; hydrogen; sodium formate; sodium hydride;
palladium on activated charcoal;
In
methanol; dimethyl sulfoxide;
DOI:10.1021/jo00367a026
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 76 percent / HCl, H2 / 10percent Pd/C / methanol / 5 h / 2327.2 Torr / Ambient temperature
2: 98 percent / sodium formate / 1 h / Ambient temperature
3: 1.) NaH / 1.) DMF, 0 deg C, 30 min, 2.) DMF, 0 deg C, 1 h
4: 77 percent / methanolic HBr / methanol / 1 h / Heating
With
hydrogenchloride; hydrogen bromide; hydrogen; sodium formate; sodium hydride;
palladium on activated charcoal;
In
methanol;
DOI:10.1021/jo00367a026
