C₁₃H₉BrFN

Base Information

• Chemical Name: C₁₃H₉BrFN
• CAS No.: 405284-40-4
• Molecular Formula: C₁₃H₉BrFN
• Molecular Weight: 278.124
• Mol file: 405284-40-4.mol

Synonyms:C₁₃H₉BrFN

Chemical Property of C₁₃H₉BrFN

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₃H₉BrFN

There total 1 articles about C₁₃H₉BrFN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-fluorobenzaldehyde (459-57-4) + 2-bromoaniline (615-36-1) → C13H9BrFN (405284-40-4)

Guidance literature:

With magnesium sulfate; In dichloroethane; at 65 ℃;

DOI:10.1016/j.tetlet.2012.02.096

Reference yield:

C13H9BrFN (405284-40-4) + 2-methylallylmagnesium chloride (5674-01-1) → C17H17BrFN

Guidance literature:

C₁₃H₉BrFN; 2-methylallylmagnesium chloride; With magnesium sulfate; In tetrahydrofuran; at 0 ℃;

With ammonium chloride; In tetrahydrofuran;

DOI:10.1016/j.tetlet.2012.02.096

Reference yield:

C13H9BrFN (405284-40-4) → C31H29FN2O3

Guidance literature:

Multi-step reaction with 3 steps

1.1: magnesium sulfate / tetrahydrofuran / 0 °C

2.1: sodium hexamethyldisilazane / tetrahydrofuran / 1 h / 0 °C

2.2: 0 - 20 °C

3.1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; potassium phosphate; tri tert-butylphosphoniumtetrafluoroborate / water; toluene / 14 h / 90 °C

With potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sodium hexamethyldisilazane; magnesium sulfate; tri tert-butylphosphoniumtetrafluoroborate; In tetrahydrofuran; water; toluene; 3.1: Heck-Suzuki cascade reaction;

DOI:10.1016/j.tetlet.2012.02.096

upstream raw materials:

4-fluorobenzaldehyde

2-bromoaniline

Downstream raw materials:

C₂₅H₂₅BrFNO