Ethyl (1S,2R,4R,5R)-4-<(2S)-2-acetoxy-2-phenylacetoxy>-2-hydroxy-5-methyl-2-(2-trimethylsilyl-3-furyl)cyclohexanecarboxylate

Base Information

Chemical Name:Ethyl (1S,2R,4R,5R)-4-<(2S)-2-acetoxy-2-phenylacetoxy>-2-hydroxy-5-methyl-2-(2-trimethylsilyl-3-furyl)cyclohexanecarboxylate
CAS No.:129312-18-1
Molecular Formula:C₂₇H₃₆O₈Si
Molecular Weight:516.664
Hs Code.:

Synonyms:Ethyl (1S,2R,4R,5R)-4-<(2S)-2-acetoxy-2-phenylacetoxy>-2-hydroxy-5-methyl-2-(2-trimethylsilyl-3-furyl)cyclohexanecarboxylate

Suppliers and Price of Ethyl (1S,2R,4R,5R)-4-<(2S)-2-acetoxy-2-phenylacetoxy>-2-hydroxy-5-methyl-2-(2-trimethylsilyl-3-furyl)cyclohexanecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Ethyl (1S,2R,4R,5R)-4-<(2S)-2-acetoxy-2-phenylacetoxy>-2-hydroxy-5-methyl-2-(2-trimethylsilyl-3-furyl)cyclohexanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Ethyl (1S,2R,4R,5R)-4-<(2S)-2-acetoxy-2-phenylacetoxy>-2-hydroxy-5-methyl-2-(2-trimethylsilyl-3-furyl)cyclohexanecarboxylate

There total 1 articles about Ethyl (1S,2R,4R,5R)-4-<(2S)-2-acetoxy-2-phenylacetoxy>-2-hydroxy-5-methyl-2-(2-trimethylsilyl-3-furyl)cyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

: 7322-88-5
(S)-acetylmandelic acid

: (1RS,2SR,5SR)-ethyl 2,4-dihydroxy-5-methyl-2-(2'-trimethylsilyl-3'-furyl)cyclohexanecarboxylate

: Ethyl (1R,2S,4S,5S)-4-<(2S)-2-acetoxy-2-phenylacetoxy>-2-hydroxy-5-methyl-2-(2-trimethylsilyl-3-furyl)cyclohexanecarboxylate

: 129312-18-1
Ethyl (1S,2R,4R,5R)-4-<(2S)-2-acetoxy-2-phenylacetoxy>-2-hydroxy-5-methyl-2-(2-trimethylsilyl-3-furyl)cyclohexanecarboxylate

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In dichloromethane; for 16h; Yield given; Ambient temperature;
DOI:10.1039/a605894i

Reference yield: 97.0%

: 129312-18-1
Ethyl (1S,2R,4R,5R)-4-<(2S)-2-acetoxy-2-phenylacetoxy>-2-hydroxy-5-methyl-2-(2-trimethylsilyl-3-furyl)cyclohexanecarboxylate

: 188472-58-4
Ethyl (1S,2R,4R,5R)-2,4-dihydroxy-5-methyl-2-(2-trimethylsilyl-3-furyl)cyclohexanecarboxylate

Guidance literature:: With potassium carbonate; In ethanol; for 16h; Ambient temperature;
DOI:10.1039/a605894i

Reference yield:

: 129312-18-1
Ethyl (1S,2R,4R,5R)-4-<(2S)-2-acetoxy-2-phenylacetoxy>-2-hydroxy-5-methyl-2-(2-trimethylsilyl-3-furyl)cyclohexanecarboxylate

: (1S,2R,5R)-2-Hydroxy-5-methyl-4-oxo-2-(2-trimethylsilanyl-furan-3-yl)-cyclohexanecarboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / K₂CO₃ / ethanol / 16 h / Ambient temperature

2: 1.) DMSO, oxalyl chloride, 2.) NEt₃ / 1.) CH₂Cl₂, -78 deg C, 30 min, 2.) -78 deg C, 15 min; -78 deg C to r.t., 1 h

With oxalyl dichloride; potassium carbonate; dimethyl sulfoxide; triethylamine; In ethanol;
DOI:10.1039/a605894i