6-carbomethoxy-6-(3'-butenyl)-1-(trimethylsilyl)-1,4-cyclohexadiene

Base Information

• Chemical Name: 6-carbomethoxy-6-(3'-butenyl)-1-(trimethylsilyl)-1,4-cyclohexadiene
• CAS No.: 307001-13-4
• Molecular Formula: C₁₅H₂₄O₂Si
• Molecular Weight: 264.44
• Mol file: 307001-13-4.mol

Synonyms:6-carbomethoxy-6-(3'-butenyl)-1-(trimethylsilyl)-1,4-cyclohexadiene

Chemical Property of 6-carbomethoxy-6-(3'-butenyl)-1-(trimethylsilyl)-1,4-cyclohexadiene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-carbomethoxy-6-(3'-butenyl)-1-(trimethylsilyl)-1,4-cyclohexadiene

There total 1 articles about 6-carbomethoxy-6-(3'-butenyl)-1-(trimethylsilyl)-1,4-cyclohexadiene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1-bromo-4-butene (5162-44-7) + methyl o-(trimethylsilyl)benzoate (71504-29-5) → 6-carbomethoxy-6-(3'-butenyl)-1-(trimethylsilyl)-1,4-cyclohexadiene (307001-13-4)

Guidance literature:

With penta-1,3-diene; ammonia; lithium; In tetrahydrofuran; tert-butyl alcohol; at -78 ℃; for 1h;

DOI:10.1021/jo000209v

Reference yield:

6-carbomethoxy-6-(3'-butenyl)-1-(trimethylsilyl)-1,4-cyclohexadiene (307001-13-4) → (1-but-3-enyl-2-trimethylsilanyl-cyclohexa-2,5-dienyl)-methanol

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 0 ℃; for 0.5h;

DOI:10.1021/jo000209v

Reference yield:

6-carbomethoxy-6-(3'-butenyl)-1-(trimethylsilyl)-1,4-cyclohexadiene (307001-13-4) → 6-acetoxymethyl-6-(3'-butenyl)-1-(trimethylsilyl)-1,4-cyclohexadiene (307001-18-9)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄ / diethyl ether / 0.5 h / 0 °C

2: 380 mg / pyridine; DMAP / 20 °C

With pyridine; dmap; lithium aluminium tetrahydride; In diethyl ether; 1: Reduction / 2: Acylation;

DOI:10.1021/jo000209v

upstream raw materials:

1-bromo-4-butene

methyl o-(trimethylsilyl)benzoate

Downstream raw materials:

6-acetoxymethyl-6-(3'-butenyl)-1-(trimethylsilyl)-1,4-cyclohexadiene