2,2'-Methanediylbis(4-chloro-6-methylphenol)

Base Information

• Chemical Name: 2,2'-Methanediylbis(4-chloro-6-methylphenol)
• CAS No.: 57693-35-3
• Molecular Formula: C₁₅H₁₄Cl₂O₂
• Molecular Weight: 297.181
• European Community (EC) Number: 654-465-5
• NSC Number: 77122
• DSSTox Substance ID: DTXSID30291681
• Nikkaji Number: J802.062K
• Wikidata: Q82029705
• Mol file: 57693-35-3.mol

Synonyms:57693-35-3;2,2'-methanediylbis(4-chloro-6-methylphenol);4-chloro-2-[(5-chloro-2-hydroxy-3-methylphenyl)methyl]-6-methylphenol;2,2'-Methylenebis-(4-chloro-6-methyl-phenol);Phenol, 2,2'-methylenebis[4-chloro-6-methyl-;NSC77122;2,2'-Methylenebis(4-chloro-6-methylphenol);SCHEMBL67802;HL-1;DTXSID30291681;PLYLXUREZURVOA-UHFFFAOYSA-N;BDBM420281;NSC-77122;AKOS024332413;Phenol, 4-chloro-2-[(5-chloro-2-hydroxy-3-methylphenyl)methyl]-6-methyl-

Chemical Property of 2,2'-Methanediylbis(4-chloro-6-methylphenol)

Chemical Property:

• Boiling Point: 435.9°Cat760mmHg
• Flash Point: 217.4°C
• Density: 1.337g/cm³
• XLogP3: 5.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 296.0370851
• Heavy Atom Count: 19
• Complexity: 272

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=CC(=C1O)CC2=C(C(=CC(=C2)Cl)C)O)Cl

Technology Process of 2,2'-Methanediylbis(4-chloro-6-methylphenol)

There total 1 articles about 2,2'-Methanediylbis(4-chloro-6-methylphenol) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2-methyl-4-chlorophenol (1570-64-5) → 4,4'-dichloro-6,6'-dimethyl-2,2'-methanediyl-di-phenol (57693-35-3)

Guidance literature:

With sulfuric acid; acetic acid; at 40 ℃;

Reference yield:

4,4'-dichloro-6,6'-dimethyl-2,2'-methanediyl-di-phenol (57693-35-3) → 2-Hydroxy-2'-(2,3-dihydroxy-propoxy)-3,3'-dimethyl-diphenylmethan (98782-38-8)

Guidance literature:

Multi-step reaction with 2 steps

1: Raney-Ni

2: NaOEt / ethanol / Heating

With sodium ethanolate; nickel; In ethanol;

Reference yield:

4,4'-dichloro-6,6'-dimethyl-2,2'-methanediyl-di-phenol (57693-35-3) + 3-monochloro-1,2-propanediol (96-24-2) → 5,5'-Dichlor-2-hydroxy-2'-(2,3-dihydroxy-propoxy)-3,3'-dimethyl-diphenylmethan (99117-71-2)

Guidance literature:

With sodium ethanolate; In ethanol; Heating;

upstream raw materials:

formaldehyd

2-methyl-4-chlorophenol

Downstream raw materials:

bis[2-hydroxy-3-methylphenyl]methane

5,5'-Dichlor-2-hydroxy-2'-(2,3-dihydroxy-propoxy)-3,3'-dimethyl-diphenylmethan

2-Hydroxy-2'-(2,3-dihydroxy-propoxy)-3,3'-dimethyl-diphenylmethan