(3S)-2-hydroxy-2-(benzoyloxymethyl)butane-1,3,4-triyl trisbenzoate

Base Information

• Chemical Name: (3S)-2-hydroxy-2-(benzoyloxymethyl)butane-1,3,4-triyl trisbenzoate
• CAS No.: 1339943-12-2
• Molecular Formula: C₃₃H₂₈O₉
• Molecular Weight: 568.58
• Mol file: 1339943-12-2.mol

Synonyms:(3S)-2-hydroxy-2-(benzoyloxymethyl)butane-1,3,4-triyl trisbenzoate

Chemical Property of (3S)-2-hydroxy-2-(benzoyloxymethyl)butane-1,3,4-triyl trisbenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3S)-2-hydroxy-2-(benzoyloxymethyl)butane-1,3,4-triyl trisbenzoate

There total 5 articles about (3S)-2-hydroxy-2-(benzoyloxymethyl)butane-1,3,4-triyl trisbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(3S)-2-hydroxymethylbutane-1,2,3,4-tetrol (10592-17-3) + benzoyl chloride (98-88-4) → (3S)-2-hydroxy-2-(benzoyloxymethyl)butane-1,3,4-triyl trisbenzoate (1339943-12-2)

Guidance literature:

With pyridine; at 0 - 20 ℃; for 12h;

DOI:10.1016/j.tet.2011.08.088

Reference yield:

C13H18O6 → (3S)-2-hydroxy-2-(benzoyloxymethyl)butane-1,3,4-triyl trisbenzoate (1339943-12-2)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium periodate / methanol; water / 20 °C

2: sodium tetrahydroborate / methanol / 0.5 h / 20 °C

3: 20% palladium hydroxide on charcoal; hydrogen / methanol / 24 h / 20 °C

4: pyridine / 12 h / 0 - 20 °C

With pyridine; sodium tetrahydroborate; sodium periodate; 20% palladium hydroxide on charcoal; hydrogen; In methanol; water;

DOI:10.1016/j.tet.2011.08.088

Reference yield:

2,3-O-benzylidene-3-C-(hydroxymethyl)-D-erythrofuranose → (3S)-2-hydroxy-2-(benzoyloxymethyl)butane-1,3,4-triyl trisbenzoate (1339943-12-2)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium tetrahydroborate / methanol / 0.5 h / 20 °C

2: 20% palladium hydroxide on charcoal; hydrogen / methanol / 24 h / 20 °C

3: pyridine / 12 h / 0 - 20 °C

With pyridine; sodium tetrahydroborate; 20% palladium hydroxide on charcoal; hydrogen; In methanol;

DOI:10.1016/j.tet.2011.08.088

upstream raw materials:

[(5S)-2-phenyl-1,3-dioxolane-4,4,5-triyl]trimethanol

(3S)-2-hydroxymethylbutane-1,2,3,4-tetrol

benzoyl chloride

Refernces