benzyl 2-nitrophenyl sulphone

Base Information

• Chemical Name: benzyl 2-nitrophenyl sulphone
• CAS No.: 32018-42-1
• Molecular Formula: C₁₃H₁₁NO₄S
• Molecular Weight: 277.301
• Mol file: 32018-42-1.mol

Synonyms:benzyl 2-nitrophenyl sulphone

Chemical Property of benzyl 2-nitrophenyl sulphone

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of benzyl 2-nitrophenyl sulphone

There total 8 articles about benzyl 2-nitrophenyl sulphone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1-(benzylsulfanyl)-2-nitrobenzene (22057-44-9) → benzyl 2-nitrophenyl sulphone (32018-42-1)

Guidance literature:

With dihydrogen peroxide; In acetic acid; 1.) below 80 deg C, 80 min 2.) reflux, 2 h;

DOI:10.1002/hlca.19800630610

Reference yield: 95.0%

1-(benzylsulfanyl)-2-nitrobenzene (22057-44-9) → 2-nitrophenyl benzyl sulfoxide (35804-36-5) + benzyl 2-nitrophenyl sulphone (32018-42-1)

Guidance literature:

With C₄₀H₃₂CuN₂O₂S₂; dihydrogen peroxide; In water; acetonitrile; at 20 ℃; for 6h; Reagent/catalyst; Solvent; chemoselective reaction; Catalytic behavior;

DOI:10.1016/j.tetlet.2013.12.073

Reference yield:

o-nitrothiophenol (4875-10-9) → benzyl 2-nitrophenyl sulphone (32018-42-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 95.2 percent / 1.) NaOH / ethanol / 1.) 15 min 2.) reflux, 14 h

2: 97 percent / H₂O₂ / acetic acid / 1.) below 80 deg C, 80 min 2.) reflux, 2 h

With sodium hydroxide; dihydrogen peroxide; In ethanol; acetic acid;

DOI:10.1002/hlca.19800630610

upstream raw materials:

1-(benzylsulfanyl)-2-nitrobenzene

benzyl bromide

o-nitrothiophenol

benzyl chloride

Downstream raw materials:

2-Aminophenyl-benzyl-sulfon