3,3'-(1,2-phenylene)bisacrylic acid

Base Information

• Chemical Name: 3,3'-(1,2-phenylene)bisacrylic acid
• CAS No.: 110795-28-3
• Molecular Formula: C₁₂H₁₀O₄
• Molecular Weight: 218.209
• Mol file: 110795-28-3.mol

Synonyms:3,3'-(1,2-phenylene)bisacrylic acid

Chemical Property of 3,3'-(1,2-phenylene)bisacrylic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,3'-(1,2-phenylene)bisacrylic acid

There total 6 articles about 3,3'-(1,2-phenylene)bisacrylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

(E)-3-[2-{(E)-2-ethoxycarbonylvinyl}phenyl]acrylic acid ethyl ester (28839-73-8) → 3,3'-(1,2-phenylene)bisacrylic acid (110795-28-3)

Guidance literature:

With potassium hydroxide; In ethanol; for 2h; Heating;

DOI:10.1021/jm000107x

Reference yield: 13.0%

acetic anhydride (108-24-7) + o-phthalic dicarboxaldehyde (643-79-8) → 3,3'-(1,2-phenylene)bisacrylic acid (110795-28-3)

Guidance literature:

With cesium acetate; at 150 - 160 ℃; for 8h;

DOI:10.1055/s-1987-27880

Reference yield:

2,3-dibromobenzene (583-53-9) → 3,3'-(1,2-phenylene)bisacrylic acid (110795-28-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 31 percent / Et₃N; 1,3-(diphenylphosphino)propane; Pd(OAc)2 / dimethylformamide / 18 h / 100 °C

2: 91 percent / KOH / ethanol / 2 h / Heating

With palladium diacetate; potassium hydroxide; 1,3-bis-(diphenylphosphino)propane; triethylamine; In ethanol; N,N-dimethyl-formamide; 1: Heck reaction;

DOI:10.1021/jm000107x

upstream raw materials:

sodium acetate

o-phthalic dicarboxaldehyde

acetic anhydride

(E)-3-[2-{(E)-2-ethoxycarbonylvinyl}phenyl]acrylic acid ethyl ester

Downstream raw materials:

(E)-3-[2-{(E)-2-methoxycarbonylvinyl}phenyl]acrylic acid methyl ester

(E)-3-[2-{(E)-2-ethoxycarbonylvinyl}phenyl]acrylic acid ethyl ester

naphthalene

3,3'-o-phenylene-di-propionic acid diamide