(3alpha,14beta,16alpha)-14,15-Dihydro-14-hydroxyeburnamenine-14-carboxylic acid

Base Information

Chemical Name:(3alpha,14beta,16alpha)-14,15-Dihydro-14-hydroxyeburnamenine-14-carboxylic acid
CAS No.:28152-73-0
Deprecated CAS:6880-34-8,53418-29-4
Molecular Formula:C20H24 N2 O3
Molecular Weight:340.422
Hs Code.:
European Community (EC) Number:248-870-2
DSSTox Substance ID:DTXSID00950899
Nikkaji Number:J250.665C
Mol file:28152-73-0.mol

Synonyms:28152-73-0;Vincaminic acid;(3alpha,14beta,16alpha)-14,15-Dihydro-14-hydroxyeburnamenine-14-carboxylic acid;cis-Vincaminic acid;(+)-Vincaminic acid;EINECS 248-870-2;VINCAMINE IMPURITY 1;(15S,17S,19S)-15-ethyl-17-hydroxy-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraene-17-carboxylic acid;VINCAMINEIMPURITY1;DTXSID00950899;AKOS015842021;14-Hydroxy-14,15-dihydroeburnamenine-14-carboxylic acid;(3alpha,14S,16alpha)-14,15-Dihydro-14beta-hydroxyeburnamenine-14-carboxylic acid

Suppliers and Price of (3alpha,14beta,16alpha)-14,15-Dihydro-14-hydroxyeburnamenine-14-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
VincaminicAcid
10mg
$ 1320.00

Total 15 raw suppliers

Chemical Property of (3alpha,14beta,16alpha)-14,15-Dihydro-14-hydroxyeburnamenine-14-carboxylic acid

Chemical Property:

PSA：65.70000
LogP:2.80200
XLogP3:0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:340.17869263
Heavy Atom Count:25
Complexity:583

Purity/Quality:

99%, ^*data from raw suppliers

VincaminicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(C2)(C(=O)O)O
Isomeric SMILES:CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4[C@](C2)(C(=O)O)O
Uses Vincaminic Acid is a derivative compound of Vincamine (V314030), that enhances cerebral circulation and sinus flow in dogs . Vincamine is often used as a nootropic agent to combat the effects of aging, or in conjunction with other nootropics (such as piracetam) for a variety of purposes. Vincamine is a peripheral vasodilator that increases blood flow to the brain.

Technology Process of (3alpha,14beta,16alpha)-14,15-Dihydro-14-hydroxyeburnamenine-14-carboxylic acid

There total 8 articles about (3alpha,14beta,16alpha)-14,15-Dihydro-14-hydroxyeburnamenine-14-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 42971-09-5,80038-06-8
Vinpocetine

: 27773-65-5
Apovincaminic acid

: 40163-56-2
14,15-dihydro-14β-hydroxy-(3α,16α)-eburnamenine-14-carboxylic acid ethyl ester

: 3α-epivincaminic acid ethyl ester

: 14-epivincaminic acid

: 4880-88-0
vinburnine

: 28152-73-0
(3α,14β,16α)-14,15-dihydro-14-hydroxyeburnamenine-14-carboxylic acid

Guidance literature:: With hydrogenchloride; at 80 ℃; for 336h; Product distribution; Rate constant; Thermodynamic data; ln A, E_a, ΔS^<*>; degradation of vinpocetine in aqueous solutions, degradation products equilibria in solutions, effect of various pH, temperature and ionic strength, buffer catalysis, metal ion catalysis, oxygen effect, mechanism;
DOI:10.1002/jps.2600770207