C₂₀H₂₇NO₅SSi

Base Information

• Chemical Name: C₂₀H₂₇NO₅SSi
• CAS No.: 1310415-43-0
• Molecular Formula: C₂₀H₂₇NO₅SSi
• Molecular Weight: 421.59
• Mol file: 1310415-43-0.mol

Synonyms:C₂₀H₂₇NO₅SSi

Chemical Property of C₂₀H₂₇NO₅SSi

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₂₇NO₅SSi

There total 9 articles about C₂₀H₂₇NO₅SSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-tosyl-3-oxa-1-azaspiro[4.4]non-8-ene-2,7-dione (1310415-42-9) + t-butyldimethylsiyl triflate (69739-34-0) → C20H27NO5SSi (1310415-43-0)

Guidance literature:

With triethylamine; In dichloromethane; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1021/ol201236j

Reference yield:

C11H19NO3 (898404-90-5) → C20H27NO5SSi (1310415-43-0)

Guidance literature:

Multi-step reaction with 6 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 0 - 20 °C / Inert atmosphere

2.1: tetrahydrofuran; mineral oil / 0 - 20 °C / Inert atmosphere

3.1: sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / 24 h / 20 °C / Inert atmosphere

4.1: triethylamine / dichloromethane / 1.5 h / 20 °C / Inert atmosphere

4.2: 6 h / 20 °C / Inert atmosphere

5.1: pyridinium chlorochromate / dichloromethane / 4 h / 20 °C / Inert atmosphere

6.1: triethylamine / dichloromethane / -78 - 20 °C / Inert atmosphere

With sodium hydride; sodium hydrogencarbonate; triethylamine; 3-chloro-benzenecarboperoxoic acid; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane; mineral oil;

DOI:10.1021/ol201236j

Reference yield:

ethyl 1-((tert-butoxycarbonyl)amino)cyclopent-3-ene-1-carboxylate (207729-00-8) → C20H27NO5SSi (1310415-43-0)

Guidance literature:

Multi-step reaction with 7 steps

1.1: lithium borohydride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

2.1: sodium hydride / tetrahydrofuran; mineral oil / 0 - 20 °C / Inert atmosphere

3.1: tetrahydrofuran; mineral oil / 0 - 20 °C / Inert atmosphere

4.1: sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / 24 h / 20 °C / Inert atmosphere

5.1: triethylamine / dichloromethane / 1.5 h / 20 °C / Inert atmosphere

5.2: 6 h / 20 °C / Inert atmosphere

6.1: pyridinium chlorochromate / dichloromethane / 4 h / 20 °C / Inert atmosphere

7.1: triethylamine / dichloromethane / -78 - 20 °C / Inert atmosphere

With lithium borohydride; sodium hydride; sodium hydrogencarbonate; triethylamine; 3-chloro-benzenecarboperoxoic acid; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane; mineral oil;

DOI:10.1021/ol201236j

upstream raw materials:

C₁₁H₁₉NO₃

C₁₄H₁₅NO₄S

C₁₄H₁₅NO₅S

C₁₇H₂₃NO₅SSi