(E)-3,3'-(prop-1-ene-1,3-diyl)bis((trifluoromethyl)benzene)

Base Information

• Chemical Name: (E)-3,3'-(prop-1-ene-1,3-diyl)bis((trifluoromethyl)benzene)
• CAS No.: 1268238-63-6
• Molecular Formula: C₁₇H₁₂F₆
• Molecular Weight: 330.273
• Mol file: 1268238-63-6.mol

Synonyms:(E)-3,3'-(prop-1-ene-1,3-diyl)bis((trifluoromethyl)benzene)

Chemical Property of (E)-3,3'-(prop-1-ene-1,3-diyl)bis((trifluoromethyl)benzene)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-3,3'-(prop-1-ene-1,3-diyl)bis((trifluoromethyl)benzene)

There total 1 articles about (E)-3,3'-(prop-1-ene-1,3-diyl)bis((trifluoromethyl)benzene) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

Allyl acetate (591-87-7) + m-trifluoromethylphenyl iodide (401-81-0) → (E)-3,3'-(prop-1-ene-1,3-diyl)bis((trifluoromethyl)benzene) (1268238-63-6)

Guidance literature:

With tetrabutyl-ammonium chloride; palladium diacetate; triethylamine; In acetonitrile; at 120 ℃; for 16h;

DOI:10.1021/ol1031552

Reference yield: 70.0%

(E)-3,3'-(prop-1-ene-1,3-diyl)bis((trifluoromethyl)benzene) (1268238-63-6) → (E)-N,3-bis(3-(trifluoromethyl)phenyl)acrylamide (1164478-52-7)

Guidance literature:

With trimethylsilylazide; water; 2,3-dicyano-5,6-dichloro-p-benzoquinone; iron(II) chloride; In acetic acid; at 60 ℃; for 24h; chemoselective reaction; Inert atmosphere;

DOI:10.1002/anie.201106112

Reference yield: 27.0%

(E)-3,3'-(prop-1-ene-1,3-diyl)bis((trifluoromethyl)benzene) (1268238-63-6) → (E)-5-(3-(trifluoromethyl)styryl)-1-(3-(trifluoromethyl)phenyl)-1H-tetrazole (1352732-94-5)

Guidance literature:

With copper(l) iodide; trimethylsilylazide; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In acetonitrile; at 80 ℃; for 12h; chemoselective reaction; Molecular sieve; Inert atmosphere;

DOI:10.1002/anie.201105505

upstream raw materials:

Allyl acetate

m-trifluoromethylphenyl iodide

Downstream raw materials:

(E)-5-(3-(trifluoromethyl)styryl)-1-(3-(trifluoromethyl)phenyl)-1H-tetrazole

(E)-N,3-bis(3-(trifluoromethyl)phenyl)acrylamide