sodium piperidine-1-carbodithioate

Base Information

• Chemical Name: sodium piperidine-1-carbodithioate
• CAS No.: 873-57-4
• Molecular Formula: C6H11NS2
• Molecular Weight: 183.274
• European Community (EC) Number: 212-843-3
• Nikkaji Number: J52.279A
• Pharos Ligand ID: K92ZA61MNXRU
• ChEMBL ID: CHEMBL3961220
• Mol file: 873-57-4.mol

Synonyms:Sodium piperidine-1-carbodithioate;Sodium 1-piperidinecarbodithioate;Sodium piperidinedithiocarbamate;1-Piperidinecarbodithioic acid, sodium salt;EINECS 212-843-3;NSC 63883;873-57-4;CHEMBL3961220;Sodium piperidine dithiocarbamate;Sodium salt of 1-piperidinecarbodithioic acid;Dithio-1-piperidinecarboxylic acid sodium salt;Sodium,piperidine-1-carbodithioate;1-Piperidinecarboxylic acid, dithio-, sodium salt;EC 212-843-3;C6H10NS2.Na;C6H11NS2.Na;C6-H10-N-S2.Na;SCHEMBL637508;BDBM50207983;AKOS006271834;sodium (piperidine-1-carbothioyl)sulfanide;LS-114465;EN300-1085873

Chemical Property of sodium piperidine-1-carbodithioate

Chemical Property:

• Vapor Pressure: 0.106mmHg at 25°C
• Boiling Point: 221.6°C at 760 mmHg
• Flash Point: 87.8°C
• Density: 1.202g/cm³
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 183.01523595
• Heavy Atom Count: 10
• Complexity: 112

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(CC1)C(=S)[S-].[Na+]

Technology Process of sodium piperidine-1-carbodithioate

There total 6 articles about sodium piperidine-1-carbodithioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.5%

piperidine (110-89-4) + carbon disulfide (75-15-0,12122-00-8) → sodium piperidinedithiocarbamate (873-57-4)

Guidance literature:

With sodium hydroxide; at 0 ℃; for 0.25h;

DOI:10.1039/c2dt30282a

Reference yield: 41.0%

piperidine (110-89-4) + carbon disulfide (75-15-0,12122-00-8) → piperidinium piperidyldithiocarbamate (98-77-1) + sodium piperidinedithiocarbamate (873-57-4)

Guidance literature:

With sodium hydroxide; In diethyl ether;

Reference yield:

piperidine (110-89-4) + 1-(2-chloroethyl)-2-methyl-5-nitro-1H-imidazole (13182-81-5) → 2-(2-methyl-5-nitro-1-imidazolyl)ethyl-1-piperidinocarbodithioate + sodium piperidinedithiocarbamate (873-57-4)

Guidance literature:

With sodium iodide; In N-methyl-acetamide;

upstream raw materials:

piperidine

carbon disulfide

bis(piperidinothiocarbonyl)disulfide

sodium N,N'-diisopropyldithiocarbamate

Downstream raw materials:

bis(1-piperidinylthiocarbonyl)sulfide

(2-nitro-phenyl)-(piperidine-1-thiocarbonyl)-disulfane

N,N-Pentamethylen-dithiocarbamidsaeure-S-methylester

1-[4-(Bromo-phenyl-methyl)-5-oxo-[1,3]dithiolan-2-ylidene]-piperidinium; bromide

Refernces

• 1、 Kun, Walter N.,Mlowe, Sixberth,Nyamen, Linda D.,Ndifon, Peter T.,Malik, Mohammad A.,Munro, Orde Q.,Revaprasadu, Neerish. "Heterocyclic Bismuth(III) Dithiocarbamato Complexes as Single-Source Precursors for the Synthesis of Anisotropic Bi2S3Nanoparticles". . p. 13127 - 13135. Retrieved 2016.
• 2、 Awad, Ibrahim M.A.. "Heterocyclo-substituted sulfa drugs: Part XI. Novel biologically active N-(piperidino-, morpholino-, piperazino-) dithiocarbamyl-azo dyes and their chelates". . p. 219 - 251. Retrieved 2000.
• 3、 Chen, Cheng,Yang, Ke-Wu,Zhai, Le,Ding, Huan-Huan,Chigan, Jia-Zhu. "Dithiocarbamates combined with copper for revitalizing meropenem efficacy against NDM-1-producing Carbapenem-resistant Enterobacteriaceae". supporting information. . Retrieved 2021/11/20.
• 4、 Alt?nda?, Firuze Diyar,Sa?l?k, Begüm Nurpelin,Acar ?evik, Ulviye,I??kda?, ?lhan,?zkay, Yusuf,Karaca Gen?er, Hülya. "Novel imidazole derivatives as antifungal agents: Synthesis, biological evaluation, ADME prediction and molecular docking studies". . p. 887 - 894. Retrieved 2019/02/03.