1-(methoxymethyl)-9H-pyrido[3,4-b]indole

Base Information

Chemical Name:1-(methoxymethyl)-9H-pyrido[3,4-b]indole
CAS No.:55854-60-9
Molecular Formula:C₁₃H₁₂N₂O
Molecular Weight:212.251
Hs Code.:
NSC Number:149848
DSSTox Substance ID:DTXSID00419310
Nikkaji Number:J1.042.237J
Wikidata:Q82230275
Metabolomics Workbench ID:131766
ChEMBL ID:CHEMBL3400671

Synonyms:1-methoxymethyl-beta-carboline;55854-60-9;1-(methoxymethyl)-9H-pyrido[3,4-b]indole;NSC149848;1-Methoxymethyl-|A-carboline;SCHEMBL5053765;CHEMBL3400671;DTXSID00419310;HY-N11016;AKOS040734740;NSC-149848;CS-0638196

Suppliers and Price of 1-(methoxymethyl)-9H-pyrido[3,4-b]indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-(methoxymethyl)-9H-pyrido[3,4-b]indole

Chemical Property:

Vapor Pressure:3.23E-06mmHg at 25°C
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:212.094963011
Heavy Atom Count:16
Complexity:246

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COCC1=NC=CC2=C1NC3=CC=CC=C23

Technology Process of 1-(methoxymethyl)-9H-pyrido[3,4-b]indole

There total 6 articles about 1-(methoxymethyl)-9H-pyrido[3,4-b]indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.3%

: 61-54-1
tryptamine

: 10312-83-1
methoxyacetaldehyde

: 55854-60-9
1-methoxymethyl-β-carboline

Guidance literature:: With acid;
DOI:10.3987/com-98-8378

Reference yield: 13.0%

: C₁₃H₁₆N₂O₂

: 55854-60-9
1-methoxymethyl-β-carboline

Guidance literature:: C₁₃H₁₆N₂O₂; With trifluoromethylsulfonic anhydride; Triphenylphosphine oxide; In chlorobenzene; at 20 - 130 ℃; for 2h;

With manganese(IV) oxide; In chlorobenzene; at 130 ℃; for 4h;
DOI:10.1016/j.tet.2016.08.014

Reference yield:

: 61-54-1
tryptamine

: 55854-60-9
1-methoxymethyl-β-carboline

Guidance literature:: Multi-step reaction with 2 steps

1.1: pyridine / dichloromethane / 23 h / 20 °C

2.1: trifluoromethylsulfonic anhydride; Triphenylphosphine oxide / chlorobenzene / 2 h / 20 - 130 °C

2.2: 4 h / 130 °C

With pyridine; trifluoromethylsulfonic anhydride; Triphenylphosphine oxide; In dichloromethane; chlorobenzene;
DOI:10.1016/j.tet.2016.08.014