Etoglucid

Base Information

• Chemical Name: Etoglucid
• CAS No.: 1954-28-5
• Molecular Formula: C12H22 O6
• Molecular Weight: 262.303
• Hs Code.: 2910900090
• European Community (EC) Number: 217-784-7
• ICSC Number: 0204
• NSC Number: 80439
• UNII: 4F9KUA0T4D
• DSSTox Substance ID: DTXSID80862800
• Nikkaji Number: J54.369A
• Wikipedia: Etoglucid
• Wikidata: Q548286
• NCI Thesaurus Code: C489
• Metabolomics Workbench ID: 154157
• ChEMBL ID: CHEMBL460287
• Mol file: 1954-28-5.mol

Synonyms:Epodyl;Ethoglucid;Etoglucid

Chemical Property of Etoglucid

Chemical Property:

• Vapor Pressure: 6.02E-05mmHg at 25°C
• Melting Point: -15 to -11°
• Refractive Index: nD20 1.4584
• Boiling Point: 356.4°Cat760mmHg
• Flash Point: 145°C
• PSA: 61.98000
• Density: 1.157g/cm³
• LogP: -0.14960
• XLogP3: -1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 13
• Exact Mass: 262.14163842
• Heavy Atom Count: 18
• Complexity: 191

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Plastics & Rubber -> Glycidyl Ethers
• Canonical SMILES: C1C(O1)COCCOCCOCCOCC2CO2
• Inhalation Risk: No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.

Technology Process of Etoglucid

There total 3 articles about Etoglucid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

epichlorohydrin (106-89-8,24969-06-0,13403-37-7) + 2,2'-[1,2-ethanediylbis(oxy)]bisethanol (112-27-6) → ethoglucid (1954-28-5)

Guidance literature:

With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; at 40 ℃; for 0.75h;

Reference yield:

4,7,10,13-tetraoxahexadeca-1,15-diene (90736-68-8,59788-01-1) → ethoglucid (1954-28-5)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1080/10426507.2016.1255622

Reference yield:

2,2'-[1,2-ethanediylbis(oxy)]bisethanol (112-27-6) → ethoglucid (1954-28-5)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydride / tetrahydrofuran / 0 °C

2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 24 h / 20 °C

With sodium hydride; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane;

DOI:10.1080/10426507.2016.1255622

upstream raw materials:

epichlorohydrin

2,2'-[1,2-ethanediylbis(oxy)]bisethanol

4,7,10,13-tetraoxahexadeca-1,15-diene

Downstream raw materials:

1-[2-(2-{2-[2-Hydroxy-3-(4-vinyl-phenoxy)-propoxy]-ethoxy}-ethoxy)-ethoxy]-3-(4-vinyl-phenoxy)-propan-2-ol