3,5-dimethyl-4-(3-nitrophenyl)-1,4,7,8-tetrahydrodipyrazolo[3,4-b;4’,3’-e]pyridine

Base Information

• Chemical Name: 3,5-dimethyl-4-(3-nitrophenyl)-1,4,7,8-tetrahydrodipyrazolo[3,4-b;4’,3’-e]pyridine
• CAS No.: 1346445-92-8
• Molecular Formula: C₁₅H₁₄N₆O₂
• Molecular Weight: 310.315
• Mol file: 1346445-92-8.mol

Synonyms:3,5-dimethyl-4-(3-nitrophenyl)-1,4,7,8-tetrahydrodipyrazolo[3,4-b;4’,3’-e]pyridine

Chemical Property of 3,5-dimethyl-4-(3-nitrophenyl)-1,4,7,8-tetrahydrodipyrazolo[3,4-b;4’,3’-e]pyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,5-dimethyl-4-(3-nitrophenyl)-1,4,7,8-tetrahydrodipyrazolo[3,4-b;4’,3’-e]pyridine

There total 3 articles about 3,5-dimethyl-4-(3-nitrophenyl)-1,4,7,8-tetrahydrodipyrazolo[3,4-b;4’,3’-e]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

ethyl acetoacetate (141-97-9) + 3-nitro-benzaldehyde (99-61-6) → 3,5-dimethyl-4-(3-nitrophenyl)-1,4,7,8-tetrahydrodipyrazolo[3,4-b;4’,3’-e]pyridine (1346445-92-8)

Guidance literature:

With triethanolamine; ammonium acetate; sodium acetate; hydrazine hydrate; for 0.0833333h; Microwave irradiation;

DOI:10.1007/s13738-021-02178-z

Reference yield: 93.0%

3-nitro-benzaldehyde (99-61-6) + acetoacetic acid methyl ester (105-45-3) → 3,5-dimethyl-4-(3-nitrophenyl)-1,4,7,8-tetrahydrodipyrazolo[3,4-b;4’,3’-e]pyridine (1346445-92-8)

Guidance literature:

With hydrazine hydrate; ammonium carbonate; In water; at 20 ℃; for 0.3h; Green chemistry;

DOI:10.1055/s-0039-1691600

Reference yield: 92.0%

3-nitro-benzaldehyde (99-61-6) + 3-methyl-2-pyrazoline-5-one (108-26-9) → 3,5-dimethyl-4-(3-nitrophenyl)-1,4,7,8-tetrahydrodipyrazolo[3,4-b;4’,3’-e]pyridine (1346445-92-8)

Guidance literature:

With phospho sulphonic acid; ammonium acetate; In neat (no solvent); at 70 ℃; for 0.416667h; under 760.051 Torr; Microwave irradiation; Green chemistry;

DOI:10.1002/jhet.4241

upstream raw materials:

3-nitro-benzaldehyde

3-methyl-2-pyrazoline-5-one

ethyl acetoacetate

acetoacetic acid methyl ester