delta-(L-alpha-Aminoadipoyl)-L-cysteinyl-glycine

Base Information

• Chemical Name: delta-(L-alpha-Aminoadipoyl)-L-cysteinyl-glycine
• CAS No.: 9002-61-3
• Molecular Formula: C17H28
• Molecular Weight: 232.40422
• Hs Code.: 2937190000
• European Community (EC) Number: 232-660-2
• ChEMBL ID: CHEMBL1233255
• Nikkaji Number: J2.178.463J
• Wikidata: Q27461047
• Mol file: 9002-61-3.mol

Synonyms:DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-GLYCINE;HCG;Chorionic gonadotrophin;CHEMBL1233255;1ST10885;9002-61-3;Q27461047;N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinylglycine

Chemical Property of delta-(L-alpha-Aminoadipoyl)-L-cysteinyl-glycine

Chemical Property:

• Appearance/Colour: Powder
• PSA: 0.00000
• LogP: 0.00000
• Storage Temp.: 2-8°C
• Solubility.: H2O: soluble1ML/vial
• XLogP3: -4.1
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 10
• Exact Mass: 321.09945651
• Heavy Atom Count: 21
• Complexity: 403

Purity/Quality:

99% ^*data from raw suppliers

Chorionic Gonadotropin, Human ^*data from reagent suppliers

Safty Information:

• Pictogram(s): B,Xn
• Hazard Codes: B,Xn
• Statements: 63-62
• Safety Statements: 22-36-36/37

MSDS Files:

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(CC(C(=O)O)N)CC(=O)NC(CS)C(=O)NCC(=O)O
• Isomeric SMILES: C(C[C@@H](C(=O)O)N)CC(=O)N[C@@H](CS)C(=O)NCC(=O)O
• Recent ClinicalTrials: To Investigate Efficacy and Safety of a Single Injection of GenSci094 for Ovarian Stimulation Using Daily Recombinant FSH as Reference
• Recent EU Clinical Trials: A randomized, double-blinded, clinical, placebo-controlled trial on the effects of therapy with Letrozole and hUman Choriongonadotropin in male hypogonadism induced by illicit use of Anabolic androgenic Steroids on plasma reproductive hormones, fertility, withdrawal symptoms and myocardial function - The LUCAS trial
• Uses: Chorionic gonadotropin human has been used: to induce oocyte maturation in cultured folliclesalong with pregnant mare serum gonadotropin (PMSG) to induce superovulation in mice as medium component for fetal testes culture to aid steroidogenic responsiveness
• Clinical Use: Choriogonadotropin alfa is obtained by rDNA technology and is biologically and chemically identical to hCG of natural origin. It is used, like hCG of natural origin, for inducing ovulation in women with anovulatory infertility. Following proper pretreatment with a GnRH antagonist or superagonist to desensitize the pituitary, women participating in ART are treated with a folliclestimulating agent (e.g., menotropins) to effect the final maturation of the follicles within the ovaries. Ultrasonograms are used to determine proper follicle maturation before the administration of choriogonadotropin alfa to induce ovulation. A distinct advantage of this product is that it can be self-administered by the patient via SC injection.