Technology Process of 10-(2,3,4-trimethoxy-6-methylphenyl)decan-1-ol
There total 4 articles about 10-(2,3,4-trimethoxy-6-methylphenyl)decan-1-ol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
9-Decen-1-ol; 2-bromo-3,4,5-trimethoxy-1-methylbenzene;
With
palladium diacetate; triethylamine; triphenylphosphine;
at 120 ℃;
for 72h;
Inert atmosphere;
With
palladium 10% on activated carbon; hydrogen;
In
ethanol;
at 25 ℃;
for 3h;
DOI:10.1021/op200051v
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: tetrabutylammomium bromide; hydrogen bromide / water / 0.08 h / 100 °C / Microwave irradiation
2.1: potassium tert-butylate / tetrahydrofuran; toluene / 0.5 h / 0 °C
3.1: palladium diacetate; triethylamine; triphenylphosphine / 72 h / 120 °C / Inert atmosphere
3.2: 3 h / 25 °C
With
potassium tert-butylate; tetrabutylammomium bromide; hydrogen bromide; palladium diacetate; triethylamine; triphenylphosphine;
In
tetrahydrofuran; water; toluene;
3.1: Heck reaction;
DOI:10.1021/op200051v
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: potassium tert-butylate / tetrahydrofuran; toluene / 0.5 h / 0 °C
2.1: palladium diacetate; triethylamine; triphenylphosphine / 72 h / 120 °C / Inert atmosphere
2.2: 3 h / 25 °C
With
potassium tert-butylate; palladium diacetate; triethylamine; triphenylphosphine;
In
tetrahydrofuran; toluene;
2.1: Heck reaction;
DOI:10.1021/op200051v